摘要
目的对男性不育患者进行精液常规检查和血清生殖激素检测,探讨二者之间的关系及其对男性不育的影响。方法选取2014年6月至2015年2月在该院门诊就诊的42例不育男性作为研究对象,根据精液常规检查中精子密度和精子活力指标将其分为弱精子组(20例)和无精子组(22例),同时选取已生育、精液常规检查结果正常的17例男性作为对照组,测定三组研究对象5项生殖激素,包括卵泡刺激素(FSH)、黄体生成素(LH)、泌乳素(PRL)、雌二醇(E2)和睾酮(T)水平,并分别进行比较。结果弱精子组与对照组5项生殖激素水平比较,差异均无统计学意义(P>0.05);无精子组与对照组血清FSH、LH水平比较,差异均有统计学意义(P<0.05),但PRL、E2、T水平比较,差异均无统计学意义(P>0.05);无精子组与弱精子组血清FSH、LH水平比较,差异均有统计学意义(P<0.05),而PRL、E2、T水平比较,差异均无统计学意义(P>0.05)。结论男性不育患者同时进行精液常规检查和生殖激素检测很有必要,可以为病因分析和临床诊治及预后判断提供重要依据。
Objective To perform the semen routine and serum reproductive hormones detection in male infertile pa-tients and to investigate their relation and influence on male infertility. Methods Forty-two patients with male infertility in the outpatients department of our hospital from June 2014 to February 2015 were selected as the research subjects and divided into asthenospermia（20 cases） group and the azoospermia group（22 cases） according to the indicators of sperm density and sperm motility. At the same time 17 males with fertility and normal semen routine results were selected as the control group. The 5 repro-ductive hormones of follicle stimulating hormone （FSH）,luteinizing hormone （LH）,prolactin （PRL）,estradiol （E2） and testos-terone（T） levels were detected. The results of each indicator were compared. Results The 5 reproductive hormones levels had no statistical difference between the asthenospermia group and the control group （P〉0.05）;the serum FSH and LH levels had sta-tistical differences between the azoospermia group and the control group （P〈0.05）,but the PRL,E2 and T levels had no statistically significant differences between these two groups（P〉0.05）;the serum FSH and LH levels had statistical difference between as-thenospermia group and the azoospermia group,while the PRL,E2 and T levels had no statistically significant difference between these two groups（P〉0.05）. Conclusion It is necessary to simultaneously detect semen routine and reproductive hormones for the patients with male infertility,which can provide an important basis for the etiological analysis,clinical diagnosis and treatment, and prognosis judgment.
出处
《现代医药卫生》
2016年第13期1989-1990,1993,共3页
Journal of Modern Medicine & Health
