摘要
目的：了解南京中医药大学附属医院（以下简称＂我院＂）药品不良反应/事件的发生特点,促进临床合理用药。方法：对我院2014年1 786例静脉用药导致的药品不良反应/事件报告进行帕累托图分析。结果：1 786例发生药品不良反应/事件的患者中,男性826例（占46.25%）,女性960例（占53.75%）;年龄1~97岁。新发生的药品不良反应/事件有570例,占31.91%;严重的药品不良反应/事件有79例,占4.42%。帕累托图分析结果显示,药品不良反应/事件主要涉及营养药、抗微生物药、中药注射剂、神经系统用药和抗肿瘤药,临床表现以皮肤及其附件损害、局部损害和全身性损害为主。结论：临床用药应全面考虑药品不良反应/事件,合理使用各类药物,以尽量减少药品不良反应/事件的发生。
OBJECTIVE：To investigate the characteristics of adverse drug reactions /adverse drug events （ ADR/ADE） in Affiliated Hospital of Nanjing University of Traditional Chinese Medicine （ hereinafter referred to as “our hospital”） , so as to promote the rational drug use in clinic .METHODS： 1 786 cases of ADR/ADE induced by intravenous medication in ward were analyzed by pareto diagram .RESULTS： There were 1 786 cases , including 826 males （46.25%） and 960 females （53.75%）.Patient of the oldest was 97 years old, and the youngest was 1 year old. 570 cases of ADR/ADE were new , accounting for 31.91%.79 cases of ADR/ADE were severe , accounting for 4.42%. According to pareto diagram , ADR/ADE involved nutraceuticals , antimicrobial drugs , traditional Chinese medicine injection ,nervous system drugs and anticancer drugs .The main clinical manifestations were the damage of skin and its appendages , local damage and systemic damage .CONCLUSIONS：Great attention should be paid to the development of ADR/ADE in clinic.Rational use of drugs should be emphasized to decrease the occurrence o f ADR /ADE.
出处
《中国医院用药评价与分析》
2016年第6期832-835,共4页
Evaluation and Analysis of Drug-use in Hospitals of China
关键词
药品不良反应
药品不良事件
帕累托图分析
合理用药
Adverse drug reactions
Adverse drug events
Pareto diagram analysis
Rational drug use
