摘要
目的探讨分析潮汕地区14种呼吸道常见病毒和儿童哮喘急性发作的关系,指导临床采取防治措施。方法选取2012年4月-2013年12月因哮喘急性发作于我院就诊的98例潮汕儿童为观察组,同期哮喘非急性发作患儿45例入对照组,经过药物治疗和合理护理后观察组有52例患儿进入哮喘缓解期,采用直接免疫荧光法检测两组14种呼吸道常见病毒抗原,分析其与哮喘急性发作的关系。结果 98例哮喘急性发作儿童中,RSV感染14例(14.3%),HMPV感染11例(11.2%),HRV感染9例(9.2%),ADV感染7例(7.2%),FLUA感染6例(6.1%),PIVⅢ感染5例(5.1%),FLUB感染2例(2.0%),PIVⅠ感染1例(1.0%),其他病毒感染3例(3.1%),合并感染1例(1.0%),急性发作期总感染率为60.2%,与哮喘缓解期及对照组总感染率30.8%、26.7%比较显著增高(P<0.05)。结论病毒是潮汕地区儿童哮喘急性发作的首要原因,其中以RSV、HMPV、HRV、ADV、FLUA、PIV最常见,临床医师需做好预防工作,避免哮喘急性发作。
Objective To explore and analyze the relationship between the 14 kinds of common respiratory viruses and acute attack of asthma in children in Chaoshan areaand to guide clinical preventive measures. Methods 98 cases of children in Chaoshan who were treated for acute attack of asthma in our hospital between April 2012 and December 2013 were selected as the observation group. Another 45 children with non - acute attack who were admitted in the same period were included in the control group. After drug therapy and reasonable nursing, there were 52 children with asthma in remission stage in the observation group. The direct immunofluorescence method was used to detect the 14 kinds of common respiratory virus antigens. The relationship with acute attack of asthma was analyzed. Results Among the 98 cases of children with acute attack of asthma, there were 14 cases （14. 3% ） with RSV infection, 11 cases （11.2%） with HMPV infection, 9 cases （9.2%） with HRV infection, 7 cases （7.2%） with ADV infection, 6 cases （6. 1%） with FLUA infection, 5 cases （5.1%） with PIV III infection, 2 patients （2. 0% ） with FLUB infection, 1 case （ 1.0% ） with PIVI infection, 3 cases （3.1%） with other virus infection and 1 case （1.0%） with combined infection. The total infection rate in acute attack period （60. 2% ） was significantly higher than that in asthma remission period and that in the control group （30. 8%, 26. 7% ） （P 〈 0.05 ）. Conclusion Virus is the primary cause of acute attack of asthma in children in Chaoshan area. Besides, RSV, HMPV, HRV, ADV, FLUA and PIV are the most common ones. Clinicians need to do a better job of prevention to avoid acute attack of asthma.
出处
《现代医院》
2016年第6期827-828,831,共3页
Modern Hospitals
基金
汕头市医疗卫生科技计划引导项目(编号:20150406)
关键词
潮汕地区
呼吸道常见病毒
儿童哮喘急性发作
Chaoshan Area
Common Respiratory Virus
Acute Attack of Asthma in Children
