摘要
目的研究大蒜油的降血脂功能。方法将50只wistar大鼠随机分成5组:溶剂对照组、高脂饲料组(模型对照组)及157.0、315.0、630.0 mg/kg BW 3个剂量组。经口灌胃给予实验组大鼠受试物30 d,实验末期测定血清TG、TC、HDL-C及LDL-C含量。结果在试验末期高剂量组大鼠的血清TC检测值为(2.51±0.18),与模型对照组检测值(2.87±0.19)比较明显降低,差异有统计学意义(P<0.05);高剂量组大鼠的TG测定值(1.60±0.16)与模型对照组测定值(1.94±0.22)比较明显降低,差异有统计学意义(P<0.05);各剂量组LDL-C和高HDL-C测定值与模型对照组比较未见明显差异(P>0.05)。结论通过30 d的喂养实验,血清TG、TC表达量降低,LDL-C和HDL-C未见显著变化,说明大蒜油具有辅助降血脂的功能。
Objective To study the function of reducing blood lipid of garlic oil. Methods 50 Wistar Rats were divided into five groups ： control group,hyperlipidmia（ model control group） and 157.0,315.0,630.0 mg / kg BW three dose groups. Levels of triglyceride（TG）,total cholesterol（ TC）,high density lipoprotein cholesterol（ HDL-C）,low density lipoprotein cholesterol（ LDL-C） were measured in the end of the experiment. Results In the end of the experiment,total cholesterol（ TC） of high dose group was（ 2.51 ± 0.18）,it had a significant reduse compare to model control group＇s number（ 2.87 ± 0.19）（ P 〈0.05）. The triglyceride（ TG） of high dose group＇s number（ 1.60 ± 0.16） were significantly lower than that in the model control group in the end of the experiment（ 1.94 ± 0.22）（ P 〈0.05）; compared to model control group,low density lipoprotein cholesterol（ LDL-C） and high density lipoprotein cholesterol（ HDL-C） were not significantly affected in each dose group. Conclusion After 30 days gavage,the levels of TC,TG are reduced,LDL-C and HDL-C have no significant change. Garlic oil has the function of assisting the lowering blood lipid.
出处
《中国卫生工程学》
CAS
2016年第3期247-249,共3页
Chinese Journal of Public Health Engineering
基金
吉林省医药产业发展专项基金计划项目(20130727075YY)
关键词
大蒜油
降血脂
Garlic oil
Lowering blood lipid
