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酒石酸美托洛尔片治疗慢性阻塞性肺疾病合并慢性心力衰竭临床疗效观察 被引量:7

Clinical observation of metoprolol tartrate tablets for chronic obstructive pulmonary disease combined with chronic heart failure
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摘要 目的探讨酒石酸美托洛尔片治疗慢性阻塞性肺疾病合并慢性心力衰竭的临床疗效。方法回顾性分析2012年11月至2015年11月68例慢性阻塞性肺疾病合并慢性心力衰竭患者的临床病例资料。结果治疗组的总有效率为88.24%,高于对照组的67.65%(P<0.05),治疗组的圣乔治呼吸疾病问卷评分(SGRQ)明显低于对照组,6分钟步行试验(6MWD)明显高于对照组,差异有统计学意义(P<0.001)。两组治疗前后的FEV1、FEV1/pred(%)、FEV1/FVC相比,差异无统计学意义(P>0.05)。结论酒石酸美托洛尔片治疗慢性阻塞性肺疾病合并慢性心力衰竭的临床疗效较显著,可明显改善患者生活质量,增加运动耐氧量,且未明显减低患者肺功能,值得临床推广。 Objective To investigate clinical efficacy of metoprolol tartrate tablets in the treatment of chronic obstructive pulmonary disease(COPD)with chronic heart failure(CHF).Methods Retrospective analysis was performed in clinical da-ta of 68 cases of COPD combined with CHF admitted hospital from November,2012 to November,2015.Results The total effective rate of the treatment group(88.24%)was significantly higher than that(67.65%)of the control group(P〈0.05).The scores of SGRQ in the treatment group were significantly lower than that in the control group,6-min walk distance(6MWD) was significantly higher than that in the control group,so difference was statistically significant( P0. 05).Conclusion Metoprolol tartrate tablets has significant clinical efficacy in the treatment of COPD combined with CHF,which can significantly improve patients’quality of life and increase the oxygen tolerance of movement,but can not sig-nificantly reduce patients’lung function.Thus,it is worthy of promotion in clinical practice.
作者 郭森 苏怀昆
出处 《右江医学》 2016年第3期299-301,共3页 Chinese Youjiang Medical Journal
关键词 酒石酸美托洛尔 慢性阻塞性肺疾病 心力衰竭 metoprolol tartrate tablets COPD CHF
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