摘要
目的研究女性腰椎松质骨CT值与年龄、双能X线骨密度值的相关性。方法 103例女性住院患者纳入研究对象,所有患者行腰椎骨密度与腰椎螺旋CT检查,双能X线骨密度仪（DXA）测量腰1～4椎体骨密度（BMD）和T值。CT扫描分析腰1～4椎体松质骨CT值。将所有研究对象的年龄、腰1～4椎体CT值、DXA测得BMD值及T值进行收集、整理及统计学处理。结果 1不同年龄段腰1～4椎体松质骨CT值差异具有统计学意义（F=102.5,P〈0.001）;每两个年龄段间的CT值比较差异亦具有统计学意义（P〈0.001）。组内比较腰1～4椎体之间的CT值没有统计学意义（P〉0.05）。2按T值将所有研究对象分为3组（骨量正常、骨量减少及骨质疏松症组）,各组间腰1～4椎体松质骨CT值差异具有统计学意义（F=248.6,P〈0.001）。组间两两比较,骨质疏松症组CT值〈骨量减少组CT值〈骨量正常组CT值,差异具有统计学意义（P〈0.001）。组内比较腰1～4椎体的CT值没有统计学意义（P〉0.05）。3腰1～4椎体BMD值与椎体松质骨CT值呈显著正相关（P〈0.001）。结论女性腰椎椎体的松质骨CT值随着年龄增长逐渐减低。DXA测得BMD值与腰椎椎体松质骨CT值存在显著正相关。
Objective To evaluate the correlation among CT attenuation value of cancellous bone in the lumbar vertebrae,age,and bone mineral density measured by dual-energy X-ray absorptiometry in women. Methods A total of 103 hospitalized women were enrolled in the study. CT and DXA were examined in all subjects. BMD and T-scores of the lumbar spine（ L1-L4） were measured using DXA. The CT attenuation value of cancellous bone in L1-L4 was analyzed. The data including age,CT attenuation value of cancellous bone in L1-L4,bone mineral density and T-scores of L1-L4 of all the subjects were collected and statistical analysis was performed. Results（ 1） The difference of the CT attenuation value of cancellous bone in L1-L4 among different age groups was statistically significant（ F = 102. 5,P〈 0. 001）. The CT attenuation value of cancellous bone between every two different age groups was statistically significant（ P 〈0. 001）. There was no statistical difference among the CT attenuation values of cancellous bone in L1-L4 in the same age group（ P 〈0. 05）.（ 2） All subjects were divided into 3 groups（ normal,osteopenia,and osteoporosis） according to T-scores. The difference of the CT attenuation value of cancellous bone in L1-L4 was statistically significant among the 3 groups（ F = 248. 6,P〈 0. 001）. The CT attenuation value was compared between every 2 groups. The CT attenuation value of subjects in osteoporosis group was lower than that in osteopenia group and lower than that in normal group.There was no statistical difference among the CT attenuation value of cancellous bone in L1-L4 in the same group（ P 〉0. 05）.（ 3）The CT attenuation value of cancellous bone was positively associated with BMD in L1-L4（ P〈 0. 001. Conclusion The CT attenuation value of cancellous bone in lumbar vertebrae consistently decreases with increasing age in females. BMD measured by dual-energy X-ray absorptiometry is significantly and positively correlated with CT attenuation value of cancellous bone in
出处
《中国骨质疏松杂志》
CAS
CSCD
北大核心
2016年第6期695-699,共5页
Chinese Journal of Osteoporosis
基金
新疆医科大学科研创新基金项目(XJC2013219)
关键词
CT值
骨密度
T值
年龄
女性
CT attenuation value
Bone mineral density
T-score
Age
Female
