摘要
目的探讨钎维蛋白原、载脂蛋白比值与冠状动脉病变程度的相关性。方法选取2014年3月至2015年3月符合诊断标准的冠状动脉病变患者120例，其中稳定型心绞痛（SAP组）40例，不稳定型心绞痛（UAP组）40例，急性心肌梗死（AMI组）40例。选择同期体检者40例为对照组。比较各组纤维蛋白原、载脂蛋白比值与冠状动脉病变程度的相关性。结果纤维蛋白原：AMI组与SAP组（四分距0．42比O．29）、AMI组与对照组（四分距0．42比0．51）、UAP组与SAP组（四分距0．61比0．29）、UAP组与对照组（四分距0．61比0．51）比较差异均有统计学意义（P〈0．05）。载脂蛋白比值：AMI组与SAP组（四分距0．28比O．41）、AMI组与对照组（四分距0．28比0．42）、UAP组与SAP组（四分距0．29比0．41）、UAP组与对照组（四分距0．29比0.42）比较差异均有统计学意义（P〈0．05）。结论纤维蛋白原可以作为冠心痛的独立危险因子，而且可以作为评估冠状动脉病变的程度的一个指标。载脂蛋白比值可以用来预测冠心病风险，并且可以评估冠心病及冠状动脉病变程度。
Objective To investigate the relationship between fibrinogen and apolipoprotein ratio and the degree of coronary artery disease. Methods From March 2014 to March 2015, 120 patients diagnosed by coronary artery disease were selected, 40 cases of stable angina pectoris （ SAP group）, 40 cases of unstable angina pectoris （ UAP group）, 40 cases of acute myocardial infarction （ AMI group）. Select 40 cases of the same period as the control group. The relationship between fibrinogen, apolipoprotein ratio and the degree of coronary artery lesion in each group were compared. Results The fibrinogen： AMI group compared with SAP group （ inter-quartile range 0.42 vs 0.29 ） , AMI group compared with control group（O. 42 vs O. 51 ） UAP group compared with SAP group（0.61 vs 0.29） , UAP group corn- pared with the control group（0. 61 vs 0. 51 ）, the differences were significant （P 〈 0. 05 ）. The ratio of apolipoprotein： the differences were significant between AMI group and SAP group （inter-quartile range 0. 28 vs 0. 41 ）, AMI group and control group （0.28 vs 0.42）, UAP group and SAP group （0.29 vs 0. 41 ）, UAP group and control group（0. 29 vs 0.42） ,the differences were significant（P 〈0.05）. Conclusions Fibrinogen can serve as an independent risk factor for coronary heart disease, and can be used as an assessment of indicator for coronary artery lesions. Apolipoprotein ratios can be used to predict coronary heart disease risk, assess the degree of coronary heart disease and coronary artery lesions.
出处
《中国实用医刊》
2016年第11期31-33,共3页
Chinese Journal of Practical Medicine
