摘要
目的:明确维生素D与超敏C反应蛋白(CRP)、补体C3、C4水平和慢性自发性荨麻疹(CSU)严重程度的关系。方法:检测50例CSU患者和30名健康对照者25(OH)D和超敏C反应蛋白(CRP)、补体C3、C4水平,并对患者进行病情严重程度评分(UAS7)。结果:CSU组25(OH)D血清浓度明显低于健康对照组,CSU患者CRP、C3、C4水平明显高于健康对照组。25(OH)D血清浓度与UAS7评分呈负相关,与CRP、C3、C4之间无明显相关性。结论:维生素D的水平与慢性荨麻疹病情相关。
Objective：To determine the relationship among vitamin D level,and C3,C4 and CRP concentrations and the disease severity of chronic spontaneous urticaria.Methods：Concentrations of CRP,C3,C4 and 25-hydroxyvitamin D [25（OH） D] were detected in 50 patients and 30 healthy controls.The diseaseseverity score（UAS7） was assessed clinically.Results：The level of serum 25（OH） D in CSU patients wassignificantly lower than that in controls and the concentrations of CRP,C3 and C4 were significantly higherthan those in controls.There was a negative correlation between the level of 25（OH） D and UAS7 score in thepatients and there was no correlation between the levels of 25（OH） D,and the concentration of CRP,C3 andC4.Conclusion：The serum level of 25（OH） D is associated with the severity of CSU.
出处
《中国麻风皮肤病杂志》
2016年第6期339-341,共3页
China Journal of Leprosy and Skin Diseases
关键词
荨麻疹
维生素D
补体
urticaria
vitamin D
complement
