摘要
目的探讨中医益智治呆方联合西医治疗老年痴呆症患者的临床疗效。方法回顾性分析我院2014年1月-2016年1月100例老年痴呆症患者临床病历资料及治疗情况;50例以石杉碱甲治疗者为对照组,另50例在对照组治疗基础上加用中医益智治呆方治疗,为治疗组。统计两组临床疗效,并采用简易智能量表(MMSE)、巴氏指数(BI)和Blessed痴呆量表评价患者治疗前后各项症状改善情况,并对其认知功能和记忆情况加以评价。记录两组患者治疗期间发生的不良反应。结果治疗后,治疗组治疗总有效率为94.0%,明显高于对照组的64.0%(P<0.05);治疗后,两组患者BI评分及MMSE评分均较治疗前显著增加,治疗组升高程度明显优于对照组(P<0.05)。治疗后,两组患者认知功能和词汇记忆评分均明显高于治疗前,而Blessed痴呆量表评分明显低于治疗前,且治疗组升高或下降程度均优于对照组(P<0.05)。治疗期间,治疗组不良反应发生率为6.0%,明显低于对照组30.0%(P<0.05)。结论应用中医益智治呆方联合石杉碱甲治疗老年痴呆症疗效显著且安全,值得推广应用。
OBJECTIVE To study traditional Chinese medicine combined with Western medicine educational governance spent party clinical efficacy of Alzheimer＇ s disease patients. METHODS A retrospective analysis was conducted on 100 cases of dementia in patients with clinical data and medical treatment from January 2014 to January 2016; 50 cases with Huperzine A treatment for the control group, and the other 50 cases in the control group treated based on puzzle treatment using traditional Chinese medicine treatment for dementia, for the treatment group. Statistics clinical efficacy, and the use of Mini Mental State Exam（MMSE）, the Barthel Index （BI）and Blessed Dementia Scale Evaluation of patients were applied to calculate before and after the improvement of symp- toms; and evaluated their cognitive function and memory situation. Record adverse reactions that occur during the patient treatment groups. RESULTS After treatment, the treatment group total effective rate was 94.0%, significantly higher than the control group （64.0%, P〈0.05） ; after treatment, a significant increase in both groups of patients before treatment BI score and MMSE scores were then treated group increased significantly superior degree in the control group（P〈0.05）. After treatment, the two groups of pa- tients vocabulary memory and cognitive function scores were significantly higher than these before treatment, Blessed Dementia Scale Score was significantly lower than before treatment, and the treatment group increased or decreased level than the control group（P〈 0.05）. During treatment, the incidence of adverse reactions was of the treatment group 6.0%, which was lower than the control group（30.0%, P〈0.05）. CONCLUSION Application of Chinese puzzle cure stay Co-huperzine treatment efficacy in patients with A1- zheimer＇s disease and significant security, which was worth promoting.
出处
《中国初级卫生保健》
2016年第6期68-69,共2页
Chinese Primary Health Care
关键词
中医益智治呆方
石杉碱甲
老年痴呆症
认知功能
词汇记忆
TCM formula for treating dementia
huperzine
Alzheimer＇s disease
cognitive function
vocabulary memory
