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对sST2与冠心病心力衰竭相关性的研究进展 被引量:2

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摘要 ST2蛋白是白细胞介素1(interleukin-1,IL-1)受体超家族的成员,常表现为血清可溶性ST2蛋白(sST2)和跨膜性ST2蛋白(ST2L)两种形式。白细胞介素33(IL-33)是ST2的特异性功能配体。近年来的研究表明,sST2作为一种心脏标志物,其水平的变化与动脉粥样硬化和心肌重塑密切相关,并且在对急性心肌梗死(AMI)患者和急性失代偿性心力衰竭(ADHF)患者进行诊治和预后质量评估等方面有十分重要的临床价值。本研究主要对sST2与冠心病和心力衰竭之间的关系进行综述。
出处 《当代医药论丛》 2016年第11期116-117,共2页
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