期刊文献+

热休克蛋白在白血病细胞凋亡和耐药中的分子机制 被引量:1

下载PDF
导出
摘要 热休克蛋白(hsps)是一组普遍存在于各类细胞的具同源谱功能的高度保守的蛋白。hsps的活化和异常表达涉及多个凋亡信号传导通路和凋亡调节因子,其与化疗耐药及肿瘤的发生、发展密切有关。本文着重讨论了hsp27、hsp70、hsp90等在白血病细胞耐药和抗凋亡中的作用以及可能的分子机制。
出处 《国外医学(输血及血液学分册)》 2002年第4期324-327,共4页 Foreign Medical Sciences(Section of Blood Transfusion and Heanatology)
  • 相关文献

参考文献23

  • 1Thompson CB.APOPTOSIS IN THE PATHOGENESIS AND TREATMENT OF DISEASE [Review][J],1995(5203). 被引量:3
  • 2Kojika S;Sugita K;Inukai T.查看详情,1996. 被引量:1
  • 3Tissieres A;Mitchell HK;Tracy UM.查看详情[J],1974. 被引量:1
  • 4Beckmann J S;Soller M.查看详情,1990(08). 被引量:1
  • 5Elia G;De MA;Rossi A.查看详情,1996. 被引量:1
  • 6Liu XD;Wei YD;An ZY.查看详情,1996. 被引量:3
  • 7Mifflin LC;Cohen RE.查看详情,1994. 被引量:1
  • 8Arrigo AP.查看详情,1998. 被引量:2
  • 9den Dobbelsteen DJ;Nobel CSL;Schlegel J.查看详情,1996. 被引量:1
  • 10Bauer SR;Ruiz-Hidalgo MJ;Rudikoff EK.查看详情,1998(09). 被引量:1

共引文献6

同被引文献13

  • 1Johnson WW. P-glycoprotein-mediated efflux as a major factor in the variance of absorption and distribution of drugs: modulation of chemotherapy resistance.Methods Find Exp Clin Pharmacol,2002,24:501-514. 被引量:1
  • 2Gate L, Couvreur P, Nguyen-Ba G, et al. N-methylation of anthracyclines modulates their cytotoxicity and pharmacokinetic in wild type and multidrug resistant cells.Biomed Pharmacother,2003,57:301-308. 被引量:1
  • 3Holandino C, Veiga VF, Rodrigues ML,et al. Direct current decreases cell viability but not P-glycoprotein expression and function in human multidrug resistant leukemic cells.Bioelectromagnetics,2001,22:470-478. 被引量:1
  • 4Walter RJ, Shtil AA, Roninson IB,et al. 60-Hz electric fields inhibit protein kinase C activity and multidrug resistance gene (MDR1) up-regulation.Radiat Res,1997,147:369-375. 被引量:1
  • 5Sargent JM. The use of the MTT assay to study drug resistance in fresh tumour samples.Recent Results Cancer Res,2003,161:13-25. 被引量:1
  • 6Richart J, Brunt EM, Di Bisceglie AM. Expression of P-glycoprotein and C-MOAT in human hepatocellular carcinoma: detection by immunostaining.Dig Dis Sci,2002,47:2454-2458. 被引量:1
  • 7Devarajan E, Chen J, Multani AS, et al. Human breast cancer MCF-7 cell line contains inherently drug-resistant subclones with distinct genotypic and phenotypic features. Int J Oncol, 2002,20: 913-920. 被引量:1
  • 8Chen W. Evidence of electroconformational changes in membrane proteins: field-induced reductions in intra membrane nonlinear charge movement currents. 被引量:1
  • 9Sundaram J, Mellein BR, Mitragotri S. An experimental and theoretical analysis of ultrasound-induced permeabilization of cell membranes. Biophysical J, 2003,84: 3087-3101. 被引量:1
  • 10郭伟剑,于尔辛,郑颂国,沈兆忠,罗建民.电化学治疗对具多药耐药表型的人乳腺癌细胞MCF-7^(adr)的作用[J].中国癌症杂志,2000,10(1):65-67. 被引量:3

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部