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复方玄驹胶囊联合抗生素治疗慢性前列腺炎临床对照试验的Meta分析 被引量:2

Meta-analysis of Compound Xuanju Capsule Plus Antibiotics for Treating Patients with Chronic Prostatitis
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摘要 目的:系统评价复方玄驹胶囊治疗慢性前列腺炎的临床疗效。方法:计算机检索CNKI中国知网(总库),维普数据库,Pub Med,Cochrane图书馆。由2名评价者独立对纳入文献进行信息录入、质量评价。采用Rev Man 5.2软件进行Meta分析。结果:共纳入10个临床随机对照试验,包括1 506例患者。结果显示,复方玄驹胶囊联合抗生素与抗生素组治疗慢性前列腺炎临床疗效相比有统计学意义[OR=2.86,95%CI(2.28,3.58),P<0.000 01]。结论:现有证据表明,复方玄驹胶囊联合抗生素治疗慢性前列腺炎临床疗效优于单用抗生素组。但上述结论尚需大样本高质量临床试验加以证实。 Objective: To systemically assess the clinical efficacy of compound Xuanju capsule for chronic prostatitis. Method: We systemically searched China National Knowledge Infrastructure( CNKI),VIP Database,Pub Med and Cochrane Library for clinical trials. The information was recorded and the methodological quality of the included trials was assessed by two reviewers independently,and the valid data was analyzed by Rev Man 5. 2 software. Result: The 10 randomized control trials involving 1 506 patients were included in the study. Meta-analysis showed that there was statistically significant difference in clinical efficacy between compound Xuanju capsule plus antibiotics group and the antibiotics alone group in the treatment of chronic prostatitis [OR =2. 86,95% CI( 2. 28,3. 58),P〈0. 000 01]. Conclusion: The current evidence showed that,the compound Xuanju capsule combined with antibiotics in the treatment of chronic prostatitis was more effective than antibiotics alone. However,large and high-quality clinical trials are still required for verification.
出处 《中国实验方剂学杂志》 CAS CSCD 北大核心 2016年第11期194-197,共4页 Chinese Journal of Experimental Traditional Medical Formulae
基金 新疆维吾尔自治区自然科学基金项目(2014211C021)
关键词 复方玄驹胶囊 抗生素 慢性前列腺炎 系统评价 META分析 compound Xuanju capsule antibiotics chronic prostatitis systematic review Meta-analysis
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