摘要
目的测定头孢他啶与5%葡萄糖注射液配伍的稳定性。方法模拟临床实际用药情况,将注射用头孢他啶与5%葡萄糖注射液配伍后,在11℃和25℃分别考察其溶液外观、颜色、澄清度、p H值、有关物质、5-HMF以及含量的变化情况。结果配伍溶液在8 h内较稳定,含量下降约1%,总杂质约增加0.3%,p H值下降约0.2。结论该实验结果可供临床配伍使用时参考。
Objective To study the stability of ceftazidime mixed with 5% glucose. Methods Simulate actual clinical drug case, after injection of ceftazidime and 5% Glucose Injection,investigate the changes in its solution appearance,color,clarity,pH,related substances, 5-HMF and Content at 11℃ and 25℃.Results Compatible solution was stable over 8 hours,Content decreased by 1%,Total impurities increased by about 0.3%,pH value decreased by about 0.2 . Conclusion The reference results for clinical use compatibility.
出处
《中国继续医学教育》
2016年第13期155-156,共2页
China Continuing Medical Education
