摘要
目的分析妇科恶性肿瘤术后并发下肢深静脉血栓的形成机制，探讨有效的预防和治疗对策。方法回顾性分析22例妇科恶性肿瘤术后并发下肢深静脉血栓患者的临床资料，术后根据患者的具体情况选择手术治疗或保守治疗，观察治疗后的临床疗效。结果22例患者中行手术治疗者6例，行保守治疗者16例。治疗后痊愈18例，有效3例，无效1例，治疗后患者凝血酶时间（TT）、凝血酶原时间（PT）、部分凝血活酶时间（APTT）以及纤维蛋白原水平（Fbg）水平分别为（24．17±2．13）s、（18．25±2．13）s、（31．68±10．30）S以及（2．26±0．52）g／L，较治疗前的（14．62±6．48）s、（12．27±1．63）s、（19．33±7．26）s以及（3．59±0．57）g／L有显著改善（t=10．362、9．774、12．281、8．462，P=0．028、0．032、0．012、0．029）；出院后随访3个月，无LDVT复发病例。结论妇科恶性肿瘤患者术后发生下肢深静脉血栓的风险较高，临床应积极的进行预防，一旦确诊及时采取有效的干预措施，以改善患者预后。
Objective To analyze the pathogenesis and prevention and treatment of limb deep venous thrombosis complicated by postoperative gynaecologieal malignant tumours. Methods A retrospective analysis of 22 cases with limb deep venous thrombosis complicated by postoperative gynaecological malignant tumours in our hospital were analyzed. According to the situation of patients, surgery or conservative treatment was conducted. The clinical efficacy after treatment was observed. Results In 22 cases ,6 cases underwent surgical treatment, 16 cases underwent conservative treatment. After treatment, 18 cases were cured ,3 cases were effective, 1 case ineffective. After treatment, the TT, Pt, APTT and FBG levels were （24.17 ±2.13）s, （18.25 ±2.13）s, （31.68 ± 10.30）s and （2.26 ±0.52） g/L,whieh were all better than before treatment, the differences were statistically significant（ t = 10. 362,9. 774,12. 281,8. 462, P = 0. 028,0. 032,0.012,0. 029）. Followed up for 3 months, no recurrence of LDVT was observed. Conclusion The cases of gynecological malignant tumor have higher risk of limb deep vein thrombosis, we should taken prevention actively, once diagnosed should take effective intervention measures to improve the prognosis.
出处
《中国基层医药》
CAS
2016年第11期1656-1659,共4页
Chinese Journal of Primary Medicine and Pharmacy
基金
浙江省三门县科技计划项目（1413）
关键词
妇科恶性肿瘤
下肢深静脉血栓
发病机制
预防
治疗
Gynecological malignant tumor
Limb deep venous thrombosis
Pathogenesis
Prevention
Treatment
