摘要
目的：探讨糖化血红蛋白（HbAlc）检测在妊娠期糖尿病诊断上的价值。方法：对我院2014年1月-2014年12月产科门诊建卡系统产前检查的孕妇441例分别进行糖负荷实验（GCT）、空腹血糖（FPG）和糖化血红蛋白水平检测，根据孕周分为妊娠早期组（n=209）和妊娠中期组（n=232），以最终诊断结果为金标准，观察HbAlc在妊娠期糖尿病诊断上的价值。结果：HbAlc检查结果显示，妊娠早期组阳性率为7.66%，妊娠中期组阳性率为9.05%，阳性检出率高于GCT和FPG。HbAlc在妊娠早期的准确性为93.78%（196/209），敏感性为90.24%（16/18），特异性为94.0%（180/191）；在妊娠中期的准确性为95.69%（222/232），敏感性为95.69%（22/23），特异性为95.77%（200/209）；均高于GCT和FPG（P＜0.05）。结论：糖化血红蛋白操作简便，重复性好，在孕早期和中期敏感性均较高，具有较高的诊断价值。
Objective：to study the glycosylated hemoglobin （HbAlc） the value of the test in diagnosing gestational diabetes. Methods：from January 2014 to December 2014 obstetrics outpatient JianKa system antenatal examination of pregnant women, 441 cases of sugar load experiments respectively （GCT）, fasting plasma glucose （FPG） and glycosylated hemoglobin level detection, according to gestational age is divided into the early weeks of pregnancy group （n = 209） and the middle of a pregnancy group （n = 232）, with the final diagnosis as the gold standard, observe HbAlc value in diagnosing gestational diabetes.Results： HbAlc test results show that the early weeks of pregnancy group, positive rate was 7.66%, positive rate was 9.05%, the middle of a pregnancy group positive detection rate is higher than the GCT and FPG. HbAlc in the first trimester of pregnancy was 93.78% （196/209）, the accuracy of sensitivity was 90.24% （16/18）, specificity of 94.0% （180/191）; In the middle of a pregnancy was 95.69% （222/232）, the accuracy of sensitivity was 95.69% （22/23）, specificity of 95.77% （200/209）; Were higher than in GCT and FPG （P〈 0.05）.Conclusions：the glycated hemoglobin easy operation, good repeatability, mid and high sensitivity in the early stages of pregnancy, has high diagnostic value.
出处
《医学检验与临床》
2016年第2期26-27,30,共3页
Medical Laboratory Science and Clinics
关键词
糖化血红蛋白
妊娠期糖尿病
诊断
价值
Glycosylated hemoglobin
Gestational diabetes mellitus. Diagnosis
Value
