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betatrophin与β细胞增殖 被引量:1

Betatrophin and beta cell proliferation
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摘要 betatrophin为一种新发现的分泌蛋白,主要在肝脏和脂肪组织中表达。目前大部分研究提示betatrophin可显著、特异性地促进β细胞增殖,从而改善机体对糖的耐受。但有研究不支持以上观点,betatrophin对β细胞的确切作用、作用机制、影响因素等有待进一步研究。 Betatrophin is a newly discovered protein mainly expressed in liver and adipose tissues. Most research suggests that betatrophin can significantly and specifically promote the proliferation of beta cells, thereby improving the tolerance to glucose. However, some opposing views have also been proposed, the exact role of betatrophin on beta cells, mechanism of action, influence factors and so on need further research.
出处 《中国新药与临床杂志》 CAS CSCD 北大核心 2016年第5期314-318,共5页 Chinese Journal of New Drugs and Clinical Remedies
关键词 糖尿病 胰岛素分泌细胞 细胞增殖 betatrophin diabetes mellitus insulin- secretin cell cell proliferation betatrophin
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