摘要
目的调查老年2型糖尿病(T2DM)患者肌肉减少症的发生及相关影响因素。方法165例老年T2DM患者分为肌肉减少症组(A组,24例)和非肌肉减少症组(B组,141例),收集相关资料,分析肌肉减少症发生的相关影响因素。结果肌肉减少症的患病率为14.55%。两组患者年龄、T2DM病程、BMI和HbA1c差异均有统计学意义(P〈0.05)。多因素Logistic回归结果示,年龄[OR=4.251,95%CI(1.715~10.534),P〈0.05]、病程[OR=2.603,95%CI(1.180~5.744),P〈0.05]和HbA1c[OR=3.998,95%CI(1.224~13.060),P〈0.05]是老年T2DM患者肌肉减少症发生的独立影响因素。结论老年T2DM患者、糖尿病病程长且长期血糖控制不佳者容易发生肌肉减少症。
Objective To explore the prevalence and risk factors for sarcopenia in elderly type 2 diabetes mellitus(T2DM)in Zhenjiang district.Methods A total of 165 elderly patients with T2DM was divided into two groups of A(with sarcopenia,24 cases)and B(without sarcopenia,141 cases).The relevant data were collected and the factors related to sarcopenia were analyzed.Results The prevalence of sarcopenia was 14.55%.The differences of age,BMI,HbA1c and diabetic course were all significant between two groups(P〈0.05).The multiivariate unconditional Logisitic regression analysis showed that Age[OR=4.251,95%CI(1.715-10.534),P〈0.05],diabetic course[OR=2.603,95%CI(1.180-5.744),P〈0.05]and HbA1c[OR=3.998,95%CI(1.224-13.060),P〈0.05]were the independent influential factors for sarcopenia in elderly patients with T2DM.Conclusion Sarcopenia occurrs easily in the T2DM patients with elderly age,long diabetic course and poorly control of high blood glucose.
出处
《江苏医药》
CAS
2016年第10期1144-1146,共3页
Jiangsu Medical Journal
基金
镇江市科技计划(社发科技支撑)项目(SH2014082)
关键词
2型糖尿病
肌肉减少症
老年
Type 2 diabetes mellitus
Sarcopenia
Geriatrics