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同轴静电纺丝法制备PVA-胶原微纳米纤维 被引量:3

Preparation of PVA-collagen micro-nano fibers by coaxial electrospinning
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摘要 通过同轴静电纺丝技术,制备以胶原为壳层而PVA为核层的微纳米纤维,研究壳层胶原溶液的浓度和同轴静电纺丝工艺参数对PVA-胶原微纳米纤维形貌的影响。研究结果表明:壳层胶原溶液浓度越大,越容易获得串珠状PVA-胶原微纳米纤维;当纺丝电压为15~20kV,纺丝距离为15~20cm,壳层胶原溶液流速为0.1mL/h时,可以获得表面相对光滑的微纳米纤维。 In this paper, the PVA-collagen micro-nano fibers were prepared by coaxial electrospinning technique. The effects of collagen concentration and parameters of the coaxial electrospinning process on the morphology of PVA-collagen were investigated. Results show that the greater shell collagen concentration is, the more easily obtained beaded PVA-collagen micro-nano fibers;when the spinning voltage is 15~20 kV, the spinning distance is 15~20 cm, and the flow rate of shell collagen solution is 0. 1 mL/h, micro-nano fibers with relatively smooth surface can be obtained.
出处 《丝绸》 CAS CSCD 北大核心 2016年第6期6-10,共5页 Journal of Silk
关键词 胶原 聚乙烯醇 静电纺丝 核壳结构 微纳米纤维 collagen PVA electrospinning core-shell structure micro-nano fibers
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  • 1JI W, YANG F, VAN DEN BEUCKEN J J J P, et al.Fibrous scaffolds loaded with protein prepared by blend orcoaxial electrospinning [J]. Acta Biomaterialia, 2010, 6(11) :41994207. 被引量:1
  • 2Y 00, H S, KIM T G, PARK T G. Surface-functionalizedelectrospun nanofibers for tissue engineering and drugdelivery [J]. Advanced Drug Delivery Review’s, 2009, 61(12) : 1033-1042. 被引量:1
  • 3ZENG J, YANG L, LIANG Q, et al. Influence of the drugcompatibility with polymer solution on the release kinetics ofelectrospun fiber formulation [J]. Journal of ControlledRelease,2005,105(1/2) :43-51. 被引量:1
  • 4SU Y, LI X, LIU S P, et al. Controlled release of dual drugsfrom emulsion electrospun nanofibrous [J]. Colloids andSurfaces B : Biointerfaces, 2009,73 : 376 -381. 被引量:1
  • 5SILL T J, V0N RECUM H A. Electrospinning: applicationsin drug delivery and tissue engineering [J] . Biomaterials,2008,29(13) : 1989-2006. 被引量:1
  • 6陈宗刚..静电纺丝制备胶原蛋白-壳聚糖纳米纤维仿生细胞外基质[D].东华大学,2007:
  • 7FULLANA M J, WNEK G E. Electrospun collagen and itsapplications in regenerative medicine[J] . Drug Delivery andTranslational Research,2012,2(5) :313-322. 被引量:1
  • 8HUANG L, APKARIAN R P, CHAIK0F E L. Highresolutionanalysis of engineered type I collagen nanofibers[J]. Scanning,2001,23(6) :372-375. 被引量:1
  • 9MATTHEWS J A, WNEK G E, SIMPS0N D G.Electrospinning of collagen nanofibers [J] .Biomacromolecules, 2002,3(2) : 232 -238. 被引量:1
  • 10BOLAND E D, MATTHEWS J A, PAWL0WSKI K J, etal. Electrospinning collagen and elastin: preliminaryvascular tissue engineering[J] . Front Biosci ,2004,9 : 14221432. 被引量:1

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