摘要
目的探讨心脑血管疾病患者血浆D-二聚体和纤维蛋白原(FIB)检测的临床意义。方法对107例冠心病患者,115例脑梗死患者及70例健康人进行血浆D-二聚体和凝血常规检测,对结果进行统计学分析。结果冠心病组和脑梗死组血浆D-二聚体和纤维蛋白原含量均高于健康对照组,差异有统计学意义,而冠心病组和脑梗死组无显著性差异,且冠心病组和脑梗死组PT、APTT及TT与健康对照组无统计学差异。结论与其他凝血指标相比,血浆D-二聚体和纤维蛋白原含量对于心脑血管疾病的监测及诊断更具有临床意义。
Objective To investigate clinic significance of plasma D-dimer and Fibrinogen（FIB）in patients with cardiovascular and cerebrovascular diseases.Methods To detect the plasma D-dimer level and coagulation parameters of107 patients with coronary heart disease,115 patients with cerebral infarction and 70 healthy people,and then analyze the data with statistical methods.Results The levels of D-dimer and FIB in plasma of the patients with cardiovascular and cerebrovascular diseases are higher respectively than those of in controls（P0.05）;the difference of the D-dimer and FIB levels between the two disease groups is not statistically significant（P0.05）;the result of PT,APTT and TT between disease groups and control is no significant difference（P0.05）.Conclusion Compared with other coagulation parameters,the concentration of plasma D-dimer and FIB play a more important role in diagnosis of the cardiovascular and cerebrovascular diseases.
出处
《中国实验诊断学》
2016年第4期616-618,共3页
Chinese Journal of Laboratory Diagnosis
关键词
冠心病
脑梗死
高凝状态
D-二聚体
纤维蛋白原
coronary heart disease
cerebral infarction
hypercoagulable state
D-dimer
fibrinogen
