摘要
目的:探讨妊娠中期孕妇(中期孕妇)血浆凝血酶原时间(PT)、活化部分凝血酶原时间(APTT)、纤维蛋白原(FIB)、凝血酶时间(TT)、D-二聚体(D-D)、纤维蛋白原降解产物(FDP)等主要凝血功能指标变化及临床意义。方法:采用Sysmex CA-7000全自动血凝仪对53例中期孕妇进行凝血功能PT、APTT、TT、D-D、FDP检测。结果:中期孕妇组PT(9.72±1.11)s、APTT(27.61±3.57)s、D-D(1.64±0.60)g/L、FDP(3.37±1.45)g/L与对照组相应指标(10.29±1.09)s、(30.06±3.93)s、(1.30±0.74)g/L、(2.38±1.67)g/L比较,差异无统计学意义(P>0.05),FIB(3.77±0.70)和TT(19.48±3.58)则明显高于对照组(2.92±0.87、17.56±2.89),差异有统计学意义(P<0.05)。结论:中期孕妇FIB和TT明显延长,其他指标也有不同程度增减改变,可能存在早期高凝状态和继发纤溶系统激活,应采取相应措施预防其并发症的发生,进一步说明其凝血功能监测的重要性。
Objective To explore the middle of a pregnancy pregnant women( mid pregnant women) plasma prothrombin time( PT),activated partial prothrombin time( APTT),fibrinogen( FIB),thrombin time( TT),D- dimer( D- D),fibrinogen degradation products( FDP),the main function of blood coagulation indexes such as change and clinical significance. Method The Sysmex CA- 7000 automatic blood coagulation instrument for mid 53 cases of pregnant women blood coagulation function of PT,APTT,TT,D- D,FDP detection. Results Middle pregnant women group PT( 9. 72 ± 1. 11) s,APTT( 27. 61 ± 3. 57) s,D- D( 1. 64 ± 0. 60) g/L,the FDP( 3. 37 ± 1. 45) g/L and control group corresponding index( 10. 29 ±1. 09) s,( 30. 06 ± 3. 93) s,( 1. 30 ± 0. 74) g / L,( 2. 38 ± 1. 67) g / L was not statistical difference( P〈0. 05),FIB( 3. 77 ±0. 70) and TT( 19. 48 ± 3. 58) was significantly higher than the control group( 2. 92 ± 0. 87,17. 56 ± 2. 89),with statistical significance( P〈0. 05). Conclusion Middle pregnant women FIB and TT extended obviously,other indicators also have different degree changes,increase or decrease possible early high coagulation state and secondary fibrinolytic system activation,corresponding measures should be taken to prevent the occurrence of its complications,further illustrate the importance of the blood coagulation function monitoring.
出处
《吉林医学》
CAS
2016年第5期1080-1081,共2页
Jilin Medical Journal
关键词
孕妇
凝血功能
高凝状态
纤溶系统
Pregnant women
Blood coagulation function
High coagulation state
Fibrinolytic system