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不同表现多囊卵巢综合征患者超声参数与内分泌指标的相关性研究 被引量:15

Correlation analysis of ultrasonic parameters and endocrine indicatorsin patients with polycystic ovary syndrome
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摘要 目的:探讨不同表现多囊卵巢综合征超声参数和内分泌指标的特征及相关性。方法:对2012年6月至2014年6月我院收治的131例多囊卵巢综合征患者的临床资料进行回顾性分析,根据体重指数分为肥胖组和非肥胖组,记录并比较两组超声参数和内分泌指标。结果:肥胖组卵巢直径、卵泡数、卵巢体积、卵泡体积、血流指数分别为(33.92±3.74)mm、(17.10±3.40)个、(15.03±2.23)cm3、(1.62±1.35)cm3、(42.26±7.05);非肥胖组卵巢直径、卵泡数、卵巢体积、卵泡体积、血流指数分别为(27.91±3.01)mm、(12.00±3.20)个、(11.72±1.80)cm3、(1.04±1.03)cm3、(33.92±6.01),两组超声参数比较,差异具有统计学意义(P<0.05)。肥胖组FINS、FSH、SHBG、TC、FAI、HOMA-IR分别为(16.83±4.95)m U/L、(4.34±2.03)U/L、(104.27±75.68)nmol/L、(2.23±1.41)nmol/L、(3.41±1.97)、(3.19±1.05);非肥胖组FINS、FSH、SHBG、TC、FAI、HOMA-IR分别为(7.43±4.76)m U/L、(6.05±1.94)U/L、(184.36±94.92)nmol/L、(1.04±0.62)nmol/L、(1.65±1.31)、(1.03±0.39),两组内分泌指标比较,差异具有统计学意义(P<0.05)。非肥胖组患者卵泡数、卵巢体积与游离雄激素指数呈正相关(r=0.389,P<0.05;r=0.412,P<0.05);肥胖组患者卵泡数与卵泡刺激素呈正相关(r=0.842,P<0.01),卵巢体积与胰岛素抵抗指数呈正相关(r=0.472,P<0.05),血流指数与游离雄激素指数呈正相关(r=0.812,P<0.01),两组患者其他超声参数与内分泌指标之间无相关性。结论:肥胖型和非肥胖型多囊卵巢综合征患者超声参数和内分泌指标特征不同。 Objectives: To study the correlation of ultrasonic parameters and endocrine indicators in patients with polycystic ovary syndrome. Methods: The clinical data of 131 patients with polycystic ovary syndrome in our hospital from June 2012 to June 2014 were retrospectively analyzed. According to BMI,they were divided into obese and non- obese groups. Ultrasound parameters and endocrine indicators of the two groups were recorded and compared. Results: Ovaries diameter,number of follicles,ovarian volume,follicle size,flow index in obese group were( 33. 92 ± 3. 74) mm,( 17. 10 ± 3. 40) months,( 15. 03 ± 2. 23) cm3,( 1. 62 ± 1. 35) cm3,( 42. 26 ±7. 05); ovarian diameter,the number of follicles,ovarian volume,follicle size,flow index in non- obese group were( 27. 91 ± 3. 01) mm,( 12. 00 ± 3. 20) months,( 11. 72 ± 1. 80) cm3,( 1. 04 ± 1. 03) cm3,( 33. 92± 6. 01); the difference in ultrasonic parameters between the two groups was statistically significant( P〈0. 05).In obese group,FINS,FSH,SHBG,TC,FAI,HOMA- IR were( 16. 83 ± 4. 95) m U / L,( 4. 34 ± 2. 03) u /L,( 104. 27 ± 75. 68) nmol / L,( 2. 23 ± 1. 41) nmol / L,( 3. 41 ± 1. 97),( 3. 19 ± 1. 05); in non- obese group,FINS,FSH,SHBG,TC,FAI,HOMA- IR were( 7. 43 ± 4. 76) m U / L,( 6. 05 ± 1. 94) u / L,( 184. 36 ± 94. 92) nmol/L,( 1. 04 ± 0. 62) nmol/L,( 1. 65 ± 1. 31),( 1. 03 ± 0. 39); the difference in endocrine indicators of the two groups was statistically significant( P〈0. 05). In non- obese group,patients follicles,ovarian volume and the free androgen index were positively correlated( r = 0. 389,P〈0. 05; r = 0. 412,P〈0. 05). In obesity group,the number of follicles and follicle- stimulating hormone were positively correlated( r = 0. 842,P〈0. 01); ovarian volume and insulin resistance index was positively correlated( r = 0. 472,P〈0. 05); flow index and free male Hormone index were positively correlated( r = 0. 812,P〈0. 01�
出处 《中国性科学》 2016年第5期63-65,共3页 Chinese Journal of Human Sexuality
基金 浙江省绍兴市科技局项目(2010D10025)
关键词 多囊卵巢综合征 超声参数 内分泌指标 相关性研究 Polycystic ovary syndrome Ultrasound parameters Endocrine targets Correlation
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