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中西医结合治疗急性加重期慢性阻塞性肺疾病临床研究 被引量:8

Integrative Treatment of Acute Exacerbation of Chronic Obstructive Pulmonary Disease
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摘要 目的:观察中西医结合治疗急性加重期慢性阻塞性肺疾病的临床疗效。方法:选取急性加重期慢性阻塞性肺疾病患者76例,采取随机数字表法,分成观察组和对照组各36例。对照组采取常规西医治疗,观察组则在对照组西医常规治疗的基础上给予中药治疗,以清热化痰、宣肺平喘为治疗原则,自拟化痰宣肺方。治疗结束比较两组的临床效果。结果:观察组治疗后FEV1、FEV1%均高于对照组,差异有统计学意义(P<0.05)。两组治疗后肺通气功能均高于治疗前,差异有统计学意义(P<0.05)。观察组治疗后咳嗽、气喘、咯痰积分均低于对照组,差异有统计学意义(P<0.05)。两组治疗后咳嗽、气喘、咯痰积分均低于治疗前,差异有统计学意义(P<0.05)。两组不良反应发生率比较,差异无统计学意义(P>0.05)。结论:中西医结合治疗急性加重期慢性阻塞性肺疾病的临床效果较单独的西医治疗更加有效,并且用药也较为安全。 Objective: To observe the clinical efficacy of integrative treatment of acute exacerbation of chronic obstructive pulmonary disease( AECOPD). Methods: 76 cases of patients with acute exacerbation of chronic obstructive pulmonary disease were randomly divided into observation group and control group,with 36 cases in each group. The control group received routine therapy; the observation group was treated with traditional Chinese medicine in addition to that of the control group,with clearing heat,reducing phlegm,freeing Lung and relieving asthma being the main treatment principle. A newly created prescription of reducing phlegm and freeing Lung was used in the treatment. The clinical efficacy of the treatments was compared. Results: After treatment,both FEV1 and FEV1% of the observation group were significantly higher than those of the control group( P〈0. 05). The pulmonary function after treatment of the two groups were significantly higher than those before the treatment( P〈0. 05). After treatment,the scores of cough,asthma and expectoration of the observation group were significantly lower than those of the control group( P〈0. 05). After treatment,the scores of cough,asthma and expectoration points of both groups were significantly lower than those before treatment( P〈0. 05). The difference of the incidence of adverse reactions of the two groups was not statistically significant( P〉0. 05). Conclusion: The clinical efficacy of integrative treatment of acute exacerbation of chronic obstructive pulmonary disease is better than that of western medicine therapy.
出处 《中医学报》 CAS 2016年第5期652-655,共4页 Acta Chinese Medicine
基金 河南省中医药科学研究专项课题重点项目(2014ZY01011)
关键词 慢性阻塞性肺疾病 清热化痰、宣肺平喘法 化痰宣肺方 chronic obstructive pulmonary disease clearing heat and reducing phlegm method freeing Lung and relieving asthma method prescription of reducing phlegm and freeing Lung
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