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2型糖尿病下肢血管病变256层CTA成像特点及危险因素分析 被引量:17

THE 256 CTA IMAGING CHARACTERISTICS AND THE RELATED RISK FACTORS IN PATIENTS WITH TYPE 2 DIABETIC LOWER EXTREMITY VASCULAR DISEASE
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摘要 目的探讨糖尿病下肢血管病变(Lower extremity arterial disease,LEAD)患者下肢血管256层螺旋CT血管造影(CT angiography,CTA)成像特点及发生危险因素。方法回顾性分析2型糖尿病150例的临床及下肢动脉256层CTA资料,分析糖尿病LEAD病变特点,比较LEAD与非LEAD一般资料差异,并对糖尿病LEAD相关危险因素进行Logistic回归分析。结果 256层CTA诊断LEAD112例,动脉狭窄程度Ⅰ级26例,Ⅱ级33例,Ⅲ级40例,Ⅳ级13例;狭窄节段血管1 156支,发生在髂总动脉89支,髂外动脉94支,髂内动脉85支,股总动脉76支,股浅动脉89支,股深动脉57支,腘动脉129支,胫前动脉165支,胫腓干77支,胫后动脉152支,腓动脉143支。LEAD组和非LEAD组性别、病程、收缩压(SBP)、舒张压(DBP)、餐后2h血糖(PBG2h)、糖化血红蛋白(HbA1C)、C反应蛋白(CRP)、低密度脂蛋白胆固醇(LDL-C)及同型半胱氨酸(Hcy)比较差异有统计学意义(P<0.05)。Logistic回归分析结果显示,HbA1C、SBP、CRP、Hcy及LDL-C与2型糖尿病LEAD明显相关。结论 256层CTA是一种简便、安全、准确的早期检出糖尿病LEAD的手段,糖尿病患者应综合管理血糖、血压、血脂等多种危险因素,以预防和延缓LEAD发生、发展。 Objective To study the 256 slice CT angiography (256- CTA) imaging characteristics in pa- tients with diabetic lower extremity vascular disease and its risk factors Methods A retrospective analysis on the 256- CTA imaging data of 130 type 2 diabetes with lower extremity arterial was performed. The DLEAD characteristics were analyzed, and clinical data were compared between the LEAD group and no LEAD group, the relative risk factors were analyzed by the logistic regression. Results The 256 - CTA could early diagnosis DLEAD and Visually evaluate the severity, and 112 cases were diagnosed. Grade I ste- nosis degree of carotid artery was 26 cases, grade ]I in 33, grade Ill in 40,and grade IV in 13. Narrow seg- mental blood vessels were 1156, there were 89 in arteria iliaca communis,94 in external iliac artery, 85 in internal iliac artery, 76 in common femoral artery, 89 in common femoral artery, 57 in femoral profound artery, 129 in arteria popliteal, 165 in anterior tibial artery, 77 in Tibial phil dry artery, 152 in arteria tibia- lis posterior, and 143 in arteria peronea. Logistic regression analysis showed that systolic blood pressure (SBP), low- density lipoprotein (LDL- C), glycated hemoglobin (HbAIC), CRP (C- reactive protein), homocysteine (Hcy) levels were the risk factors for DLEA. Conclusions The 256 - CTA is a simple, safe and accurate means of checking DLEAD. Prevention and delay DLEAD multiple risk factors should be inte- grated management of blood sugar, blood pressure and lipids.
出处 《中国煤炭工业医学杂志》 2016年第5期687-690,共4页 Chinese Journal of Coal Industry Medicine
基金 河北省卫计委青年科技课题(课题号:20150537)
关键词 糖尿病 下肢血管病变 多层螺旋CT 血管造影术 危险因素 Diabetic Lower extremities arterial disease(LEAD) Multiple slice CT angiography(MSCT) Angiography Risk factors
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