摘要
目的:探讨妊娠高血压患者血清蛋白Z(PZ)与高敏C反应蛋白(hs-CRP)水平检测的临床意义。方法:选择2011年12月到2014年12月我院收治的120例妊娠高血压患者作为实验组,同期选择100例健康产妇作为对照组。检测所有研究对象的血清PZ、hs-CRP水平,分析比较不同血压、妊娠期下各组间血清PZ与hs-CRP的差别。结果:不同程度高血压组妊娠患者血清PZ、hs-CRP水平差异具有显著性(P<0.05),随高血压程度加重,PZ水平下降、hs-CRP水平升高。实验组血清PZ水平随妊娠期发展逐渐下降,且不同妊娠期血清PZ水平均明显低于对照组(P<0.05)。实验组血清hs-CRP水平随妊娠期发展逐渐上升,且不同妊娠期血清hs-CRP水平均明显高于对照组(P<0.05)。结论:血清PZ水平降低和hs-CRP水平升高会导致孕妇血压升高,检测孕妇血清PZ与hs-CRP对预防和治疗妊娠高血压具有一定的临床意义。
Objective： To investigate the clinical significance of serum protein Z （PZ） and high sensitivity C reactive protein （hs-CRP） detection in patients with pregnancy induced hypertension. Methods： A total of 120 patients with pregnancy induced hypertension, who were admitted to Tangshan Maternal and Child Health Hospital from December 2011 to December 2014, were chosen as experiment group, and 100 contemporaneous healthy pregnancy women, as control group. The levels of serum PZ and hs-CRP in the two groups were detected, and the differences of serum PZ and hs-CRP in different blood pressures and gestation period were compared. Results The serum PZ, hs-CRP levels of different blood pressures were significantly different（P〈0.05）, the serum PZ level decreased and hs-CRP level increased along with the increase of high blood pressure. The serum PZ level gradually decreased along with the development of gestation in experiment group, and it was lower than control group in each gestation period （P〈0.05）. The serum hs-CRP level gradually increased along with the development of gestation in experiment group,and it was higher than control group in each gestation period （P〈0.05）. Conclusion： The decrease of serum PZ and increase of serum hs-CRP can lead to high blood pressure among pregnancy women, which indicates that the serum PZ and hs-CRP detection plays an important role in the prevention and treatment of pregnancy induced hypertension.
出处
《现代生物医学进展》
CAS
2016年第14期2766-2768,共3页
Progress in Modern Biomedicine
关键词
妊娠高血压
血清蛋白Z
高敏C反应蛋白
检测
临床意义
Pregnancy induced hypertension
Serum protein Z
hs-CRP
Detection
Clinical significance
