摘要
目的了解某院关节镜手术干预前后围手术期预防性抗菌药物使用情况,评价干预效果,为规范临床合理使用抗菌药物提供依据。方法2012年8月起采取措施干预围手术期抗菌药物应用,对2011年9月—2013年8月该院312例关节镜手术患者围手术期抗菌药物的使用及手术切口感染情况进行回顾性调查。结果共调查患者312例,干预前150例,干预后162例,干预前后切口感染发病率均为0。干预后抗菌药物使用率为26.54%,低于干预前的100.00%,差异有统计学意义(χ2=1.781,P<0.001)。不合理预防性使用抗菌药物的现象明显改善,平均抗菌药物费用比较,差异有统计学意义(t=3.330,P<0.001),由干预前的(1 165.69±756.33)元,下降至干预后的(32.71±119.29)元。结论干预后该院关节镜手术围手术期抗菌药物使用率明显下降,用药合理性提高,仍保持切口零感染。
Objective To investigate perioperative antimicrobial prophylaxis in arthroscopic surgery in a hospital before and after intervention,evaluate intervention efficacy,and provide evidence for the rational clinical antimicrobial application.Methods From August 2012,measures were taken to intervene perioperative antimicrobial use,perioperative antimicrobial use and surgical site infection（SSI）in 312 patients undergoing arthroscopic surgery between September 2011 and August 2013 were retrospectively surveyed.Results A total of 312 patients were investigated,pre-and post-intervention were 150 and 162 cases respectively,SSI rates were both 0before and after intervention.Antimicrobial usage rate after intervention was lower than before intervention（26.54% vs 100.00%,χ2=1.781,P〈0.001）.Irrational antimicrobial use dropped obviously;average expense of antimicrobial agents dropped from（1 165.69±756.33）yuan（RMB）before intervention to（32.71 ±119.29）yuan（RMB）after intervention（t=3.330,P〈0.001）.Conclusion Perioperative antimicrobial usage rate in arthroscopic surgery at this hospital decreased significantly after intervention,rational use of antimicrobial agents has improved,SSI rate still remains zero.
出处
《中国感染控制杂志》
CAS
北大核心
2016年第4期234-237,共4页
Chinese Journal of Infection Control
基金
湖南省科技厅项目(2012SK3200)
关键词
关节镜手术
围手术期
抗菌药物
切口感染
医院感染
干预
arthroscopic surgery
perioperative period
antimicrobial agent
surgical site infection
healthcare-associated infection
intervention
