摘要
目的探讨肺炎支原体（mycoplasma pneumonia，MP）感染与维生素D（Vitamin D，VitD）水平之间的相关性。方法以2014年7～10月间就诊的650例0～13岁人群为研究对象，采用被动凝集法检测其MP的感染情况，采用电化学发光法测定血清中VitD水平。结果研究对象的MP抗体阳性率为22．46％，MP抗体阳性组的VitD水平（中位数为28．06ng／ml，范围为8．99～64．84ng／ml）明显低于阴性组（中位数为32．48ng／ml，范围为8．54～67．31ng／ml），差异有统计学意义（u=-3．876，P=0．000）；VitD减低组的MP抗体阳性率（27．86％）明显高于VitD正常组（18．38％），差异有统计学意义（x2=8．222，P=0．004）；MP与VitD呈负相关（r=-0．180，P=0．000）。结论MP感染与VitD水平具有密切的相关性，MP感染可能导致VitD水平降低，VitD水平减低后也可能会导致MP感染。
Objective To investigate the relationship between mycoplasma pneumonia （MP） infection and vitamin D（VitD） levels. Methods Subjects in the study were 650 children aged from 0 to 13 years old,passive agglutination method was used to measure the infection of mycoplasma pneumonia, and electrochemi｜uminescence assay was used to measure VitD in serum. Results MP antibody positive rate of the subjects in the study was 22.46 % ,the VitD levels of MP infected people （median = 28.06 ng/ml, 8.99 - 64.84 ng/ml） were significantly lower and the uninfected ones （median= 32.48 ng/ml, 8.54 - 67.31 ng/ml） ,and the difference was statistically significant（U=-3. 876, P= 0. 000）. MP antibody positive rate of VitD reduce group（28.06 % ） was significantly higher than that in normal VitD group （18.38 %）, and the difference was statistically significant （x2 =8. 222 ,P=0. 004）. VitD levels were negatively correlated with MP （r= -0. 180,P=0. 000）. Conclusion The MP infection was closely related to VitD levels, MP infection may lead to reduce VitD levels,and lower the VitD levels may also lead to MP infection.
出处
《现代检验医学杂志》
CAS
2016年第2期117-119,共3页
Journal of Modern Laboratory Medicine
关键词
儿童
肺炎支原体
维生素D
children
mycoplasma pneumonia
vitamin D
