摘要
尽管儿童及青少年分化型甲状腺癌（DTC）的治愈率较高，但因儿童及青少年DTC的评估、治疗及随访缺乏规范化的指导及管理，故其过度治疗的问题仍不容忽视。目前，对大多数DTC患儿而言，全切除或次全甲状腺切除加中央区淋巴结清扫可作为推荐术式。根据术前及术后的分级，选择性使用”。I治疗。采取多学科合作及个体化治疗方案，在改善预后的同时尽可能减少不良反应。
Although children with differentiated thyroid cancer （DTC） are in a high proportion of cure, due to the absence of the standard management of the evaluation, treatment and follow-up of children with thyroid neoplasia, the aggressive therapy including total thyroidectomy followed by radioactive iodine （RAI） ablation with iodine-131 （^131I） could not be ignored. For the majority of children, total or near-total thyroidectomy is recommended. Central neck dissection is recommended for children with malignant cytology and clinical evidence of gross extrathyroidal invasion and/or loco-regional metastasis on pre-operative. Selective use of ~3~I in children with DTC was based on pre- and post-operative staging. Multi-disciplinary collaborative management is needed to improve their outcomes and to minimize adverse effects as far as possible.
出处
《中华内分泌代谢杂志》
CAS
CSCD
北大核心
2016年第4期265-268,共4页
Chinese Journal of Endocrinology and Metabolism
