摘要
目的:研究光动力治疗合并人类免疫缺陷病毒(HIV)感染的尖锐湿疣患者临床效果。方法:回顾性分析于2012年1月到2015年1月在我院确诊为尖锐湿疣合并HIV感染的24例患者。14例患者应用5-氨基酮戊酸光动力治疗,10例患者应用二氧化碳激光治疗,分别比较两组患者的完全缓解率、复发率、不良反应率。结果:两组患者的完全缓解率之间的差异无统计学意义(χ^2=0.062,P=0.875);而光动力治疗组的复发率和不良反应率分别为7.14%和21.43%,明显低于二氧化碳激光治疗组的复发率和不良反应率(60.00%和80.00%),两组在复发率和不良反应率上差异具有统计学意义(χ^2=5.538,P=0.019;χ^2=7.837,P=0.005)。结论:光动力治疗法是可以有效地治疗合并HIV感染的尖锐湿疣。
Objectives:To study the clinical effect of photodynamic therapy in treatment of HIV patients with condyloma acuminatum.Methods:24 patients diagnosed with HIV and condyloma acuminatum at our hospital from January 2012 to January 2015 were retrospectively analyzed.14 patients were treated with photodynamic therapy as the photodynamic therapy group.10 patients treated with carbon dioxide laser therapy were included in the carbon dioxide laser therapy group.The rate of complete remission,recurernce,adverse reaction of the two groups was compared.Results:The rate of recurrence and adverse reaction of photodynamic therapy group were 7.14% and21.43% respectively, obviously lower than these of the carbon dioxide laser therapy group (60.00% and80.00%),both with significantly statistical difference (χ^2= 5.538,P = 0.019;χ^2= 7.837,P = 0.005).Conclusion:Photodynamic therapy can effectively treat HIV infected patients with condyloma acuminatum.
出处
《中国性科学》
2016年第4期95-97,共3页
Chinese Journal of Human Sexuality