期刊文献+

光动力治疗尖锐湿疣合并人类免疫缺陷病毒感染患者临床研究 被引量:4

Clinical research of photodynamic therapy in treatment of HIV infected patients with condyloma acuminatum
下载PDF
导出
摘要 目的:研究光动力治疗合并人类免疫缺陷病毒(HIV)感染的尖锐湿疣患者临床效果。方法:回顾性分析于2012年1月到2015年1月在我院确诊为尖锐湿疣合并HIV感染的24例患者。14例患者应用5-氨基酮戊酸光动力治疗,10例患者应用二氧化碳激光治疗,分别比较两组患者的完全缓解率、复发率、不良反应率。结果:两组患者的完全缓解率之间的差异无统计学意义(χ^2=0.062,P=0.875);而光动力治疗组的复发率和不良反应率分别为7.14%和21.43%,明显低于二氧化碳激光治疗组的复发率和不良反应率(60.00%和80.00%),两组在复发率和不良反应率上差异具有统计学意义(χ^2=5.538,P=0.019;χ^2=7.837,P=0.005)。结论:光动力治疗法是可以有效地治疗合并HIV感染的尖锐湿疣。 Objectives:To study the clinical effect of photodynamic therapy in treatment of HIV patients with condyloma acuminatum.Methods:24 patients diagnosed with HIV and condyloma acuminatum at our hospital from January 2012 to January 2015 were retrospectively analyzed.14 patients were treated with photodynamic therapy as the photodynamic therapy group.10 patients treated with carbon dioxide laser therapy were included in the carbon dioxide laser therapy group.The rate of complete remission,recurernce,adverse reaction of the two groups was compared.Results:The rate of recurrence and adverse reaction of photodynamic therapy group were 7.14% and21.43% respectively, obviously lower than these of the carbon dioxide laser therapy group (60.00% and80.00%),both with significantly statistical difference (χ^2= 5.538,P = 0.019;χ^2= 7.837,P = 0.005).Conclusion:Photodynamic therapy can effectively treat HIV infected patients with condyloma acuminatum.
出处 《中国性科学》 2016年第4期95-97,共3页 Chinese Journal of Human Sexuality
关键词 光动力治疗 二氧化碳激光治疗 人类免疫缺陷病毒 尖锐湿疣 Photodynamic therapy Carbon dioxide laser therapy group HIV Condyloma acuminatum
  • 相关文献

参考文献15

  • 1黄熙,陈德华,杨凤元,严文杰.尖锐湿疣患者中HPV亚临床感染的病理形态和病毒型别分析[J].中华皮肤科杂志,2011,44(10):700-703. 被引量:18
  • 2路亮,徐丹,刘明斌,刘亚涛,周显凤.南昌市MSM人群五种常见STD感染状况及HIV感染影响因素分析[J].中华疾病控制杂志,2014,18(7):617-620. 被引量:17
  • 3Mchepange UO,Huang CY,Sun Y,et al.Two-step irradiance schedule versus single-dose tramadol sustained-release tablets for pain control during topical 5-aminolevulinic acid-photodynamic therapy of condyloma acuminatum in Chinese patients:a randomized comparative study.Lasers Surg Med,2014,46(5):389-395. 被引量:1
  • 4赵辨.临床皮肤病学.第3版.南京:江苏科学技术出版社,2010.1816-1820. 被引量:3
  • 5黄丹,鞠梅,钱伊弘,周平玉,唐增奇,杨夕芳,张小华,郭庆,陈崑,顾恒.20%氨基酮戊酸光动力治疗外阴尖锐湿疣量效关系临床研究[J].中华皮肤科杂志,2014,47(7):503-505. 被引量:21
  • 6Braga JC,Nadal SR,Stiepcich M,et al.Buschke-Loewenstein tumor:identification of HPV type 6 and 11.An Bras Dermatol,2012,87(1):131-134. 被引量:1
  • 7Lube GE,Aikawa NE,Tacla M,et al.Condyloma acuminatum in childhood-systemic lupus erythematosus patients.Acta Reumatológica Portuguesa,2014,39(2):182-187. 被引量:1
  • 8Leonard B,Kridelka F,Delbecque K,et al.A clinical and pathological overview of vulvar condyloma acuminatum,intraepithelial neoplasia,and squamous cell carcinoma.Biomed Res Int,2014:480573. 被引量:1
  • 9Watkins RL,Foster JL,Garcia JV.In vivo analysis of Nef's role in HIV-1 replication,systemic T cell activation and CD4(+)T cell loss.Retrovirology,2015(12):61. 被引量:1
  • 10Yokobayashi H,Sugaya M,Miyagaki T,et al.Analysis of serum chemokine levels in patients with HIV-associated eosinophilic folliculitis.J Eur Acad Dermatol Venereol,2013,27(2):e212-e216. 被引量:1

二级参考文献55

共引文献107

同被引文献44

引证文献4

二级引证文献7

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部