摘要
微流控芯片是细胞体外培养的重要平台,基于该平台所发展的器官芯片技术更因其能够模拟人体器官的复杂结构及功能而受到重视。本文从不同器官的角度介绍了近年来器官芯片技术在构建人体生理学模型、药物研发及毒理学研究中的应用,并对器官芯片技术的发展前景进行了展望。
Microfluidic chips are significant platforms of cell culture in vitro. Microfluidic chip-based organson-chips technology has received attention because it can mimic the complex structures and functions of human organs. In this review,the recent advances of organs-on-chips technology in different organs are reported including the build of human physiological models, drug discovery and toxicology research. And the development of this technology is proposed.
出处
《分析化学》
SCIE
EI
CAS
CSCD
北大核心
2016年第4期533-541,共9页
Chinese Journal of Analytical Chemistry
基金
国家“重大新药创制”科技重大专项(No.2013ZX09507005)资助~~
