摘要
肝转移(liver metastases,LTs)是影响神经内分泌肿瘤(neuroendocrine tumor,NET)患者预后的重要因素。虽然根治性手术是一种可能治愈疾病的治疗方式,但大多数患者确诊肝转移时已经错过了根治性切除的最佳时机。对于不可切除的神经内分泌瘤肝转移患者,现常用的方法有姑息性减瘤手术、射频消融、TACE/TAI/TAE、静脉化疗、放射性核素治疗,虽然治疗方法很多,但最佳的治疗方法尚有争议。近年来,有文献证实TACE/TAI/TAE治疗肝脏转移肿瘤是有效并且安全的。本文就神经内分泌肿瘤肝转移经动脉介入治疗进展与不足进行综述。
Liver metastases in patients with neuroendocrine tumors is a poor factor influencing prognosis.Radical surgery can get favorite outcome,however,at the time of diagnosis,the majority of patient cannot be completely resected.Management of patients with unresected liver metastases is various,such as palliative cytoreductive surgery,ablation,TACE/TAE/TAI,intravenous chemotherapy,peptide receptor radionuclide therapy.But the effect is controversial.In recent years,some literatures confirm TACE/TAE/TAI is safe and effective.This review makes a summary of main relevant articles,then expounds the advantages and disadvantages of transvascular interventional therapy of liver metastases in patients with neuroendocrine tumors.
出处
《西部医学》
2016年第4期585-588,F0003,共5页
Medical Journal of West China
基金
上海市科委科研课题(14411960300)
关键词
神经内分泌肿瘤
肝转移
经肝动脉化疗栓塞/灌注
Neuroendocrine tumors
Liver metastases
Transarterial chemoembolization/infusion
