摘要
动脉粥样硬化(AS)是一种慢性炎症性疾病。促炎细胞、促炎因子以及抗炎细胞、抗炎因子在此过程中发挥了重要作用,双方相互抑制,特定环境可相互促进,构成了一个复杂的炎症网络系统。平衡打破则表现为促炎活性升高和抑炎活性降低,可促进斑块的进展和不稳定,导致心血管事件。近年来白细胞介素(IL)-1家族在AS过程中的作用受到重视。依据其在AS进程中的作用,将其分为促AS家族,抗AS家族以及未归类成员。
Atheroselerosis （AS） is a chronic inflammatory disease, Proinflammatory cytokines and anti-inflammatory cytokines play an Important role in this process. They inhibition as well as promote each other, which constitute a large and complex inflammatory system. When this balance is broken, and that means proinflammatory factors play the dominant role in inflammatory process, acute cardiovascular events will happen. In recent years, the relationship between interleukin （IL）-I family attracted the attention of scientists. In this review, we divided the IL-1 family into promoting atherosclerosis members, anti-atherosclerosis members and uncategorized members.
出处
《医学与哲学（B）》
2016年第3期55-57,共3页
Medicine & Philosophy(B)
关键词
动脉粥样硬化
白介素-1
促炎因子
抗炎因子
atherosclerosis, interleukin-1 （IL-1）, inflammatory factor, antiinflammatory factor
