摘要
目的分析在普通外科手术后切口发生感染的病原菌的分布情况,并探讨其耐药率。方法以2家综合性医院和该院为研究中心,整群选取2014年3月—2015年2月行普外科手术的患者2 480例,对这些患者的资料进行回顾性分析,分析病原菌的感染情况,并对药敏实验结果进行分析。结果切口感染发生率为3.22%,其中I类切口发生感染12例,感染率为1.60%,II类切口发生感染52例,感染率为3.65%,III类切口发生感染16例,感染率为5.23%,各类型切口感染发生率对比,差异有统计学意义(P<0.05);在80例切口发生感染患者中,其中有58例的切口分泌物检测出病原菌,所占比例为70.00%,分离出菌株66株,其中革兰阴性菌40株,构成比为60.61%,革兰阳性菌24株,构成比36.36%,真菌2株,构成比3.03%;革兰阴性菌对氨苄西林、氨苄西林/舒巴坦及头孢类的耐药率均在50%以上,对此种药物的耐药性较高;革兰阳性菌氨苄西林/舒巴坦、克林霉素及青霉素G的耐药率较高。结论革兰阴性菌是普通外科手术后发生切口感染的主要病原菌,且对常用的抗菌药物具有较高的耐药率。
Objective To analyze the distribution of pathogenic bacteria infection with the incision infection affer surgical operation and to investigate the drug resistance rate. Methods A retrospective analysis was made on the data of 2480 patients who underwent department of general surgery opretion in our hospital from March 2014 to February 2015. The infection of pathogenic bacteria was analyzed, and the drug sensitivity test results were analyzed. Results Of all the patients, the incidence of incision infection was 3.22%, of which, type I incision infection occurred in 12 cases, the infection rate was1.60%, type II incision infection occurred in 52 cases, the infection rate was 3.65%, type III incision infection occurred in16 cases, the infection rate was 5.23%, the difference in the incidence of infection between various types of incision was statistically significant（P〈 0.05）. Of the 80 cases with wound infection, pathogenic bacteria were detected from the 58 cases＇ incision secretions, accounting for 70.00%; 66 strains of bacteria were isolated, including 40 strains of gram-negative bacteria, accounting for 60.61%, 24 strains of gram-positive bacteria, accounting for 36.36%, 2 strains of fungi, accounting for3.03%. Gram-negative bacteria had high resistance to such dugs as ampicillin, ampicillin / sulbactam and cephalosporins with over 50% drug resistance rate to them. Gram-positive bacteria had high resistance to ampicillin/sulbactam, clindamycin and penicillin G. Conclusion Gram-negative bacteria are the main pathogenic bacteria causing incision infection after common surgery, and they have high resistance to antibiotics.
出处
《中外医疗》
2016年第1期18-20,共3页
China & Foreign Medical Treatment
关键词
普外科手术
切口感染
病原菌
耐药率
General surgery
Incision infection
Pathogenic bacteria
Drug resistance rate
