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脊柱围手术期手术部位感染的诊断及预防研究进展 被引量:12

Progress in diagnosis and prevention of perioperative spinal surgical site infection
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摘要 脊柱术后切口部位感染可导致严重的并发症,如内固定失败、骨髓炎、假关节形成、椎间盘炎、瘫痪、败血症甚至死亡。早期诊断和积极采取预防措施对降低脊柱术后感染具有重要意义。近年来,新技术如血清淀粉样-A、氟-18-氟代脱氧葡萄糖PET/CT等不断涌现并逐渐应用于脊柱术后感染诊断,提高了诊断能力。同时,越来越多的文献报道各种预防措施应用于降低术后感染率,包括术前皮肤去定植、预防性使用抗生素、脉冲冲洗、局部应用抗生素、切口负压疗法等。本文针对脊柱手术部位感染的早期诊断及预防措施进行综述。 Surgical site infection( SSI) after spinal surgery can give rise to several serious secondary complications,such as fixation failure,osteomyelitis,pseudoarthrosis,diskitis,paralysis,sepsis,and death. Early diagnosis and positive preventive measures for SSI will be significant to reduce these possibilities. In recent years,new techniques,such as fludeoxyglucose( 18F)positron emission tomography( 18F-FDG PET / CT) and serum amyloid A,have emerged and gradually been employed in the diagnosis of postoperative infection,updating the ability to identify the presence of infection. There is an increasing body of literatures on preventive strategies,including preoperative skin decontamination,systemic prophylactic antibiotics,pulsed irrigation,prophylactic topical antimicrobials,negative pressure wound therapy and so on,which aim in reduction of SSI。The purpose of this review is to summarize the recent literatures on the early diagnosis and positive preventive measures of SSIs after adult spine surgery.
机构地区 空军总医院骨科
出处 《中国矫形外科杂志》 CAS CSCD 北大核心 2016年第7期631-635,共5页 Orthopedic Journal of China
关键词 脊柱手术 手术部位感染 进展 spinal operation surgical site infection review
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