摘要
目的评价磁共振扩散张量成像技术(diffusion tensor imaging,DTI)对脊髓型颈椎病的诊断价值。方法对20例健康志愿者和50例脊髓型颈椎病(CSM)患者行颈髓DTI。依据颈髓MRI平扫结果将CSM患者分A、B、C3组,A组17例(单纯硬膜囊受压);B组23例(颈髓受压,信号正常);C组10例(颈髓受压,T_2高信号)。分析4组颈髓的表观扩散系数(ADC)、分数各向异性值(FA)之间的差异。结果对照组(C_(2/3)、C_3/C_4、C_4/C_5、C_5/C_6、C_6/C_7)之间ADC值及FA值差异无显著性(P>0.05),平均ADC值为0.875±0.123,FA值为0.723±0.078;对照组与A组比较,ADC值、FA值差异无统计学意义(P>0.05),对照组与B、C组及A、B、C组间比较,ADC值、FA值差异均有统计学意义(P<0.05)。结论颈髓DTI较常规MRI能够早期、准确地量化脊髓型颈椎病的颈髓微结构改变。
Objective To explore the value of diffusion tensor imaging （ DTI） in the cervical spondylotic myelopathy .Meth-ods Twenty healthy volunteers and fifty with cervical spondylotic myelopathy were performed DTI .Fifty patients were divided in-to three groups according to cervical MRI scan standard , Group A had only the dura mater spinalis compressed;Group B showed the cervical spinal cord compressed , but no high signal in it;Group C had the cervical spinal cord compressed with high signal in the same level .ADC and FA values of these examinee were analyzed .Results The values of ADC and FA in the control group （C2/3, C3/C4, C4/C5, C5/C6, C6/C7） were no statistically significant differences （ P 〉0.05）, averaged ADC and FA values were 0.875 ±0.123 ×10-3 mm2/s and 0.723 ±0.078;Between the control group and the group A , there were no statistically sig-nificant differences in ADC and FA （ P 〉0.05）.There were significant differences in ADC and FA , between the control group and group B, between the control group and group C , as well as A, B, C groups respectively （ P 〈0.05）.Conclusion DTI can early and accurately quantify the changes of microstructure in the cervical spondylotic myelopathy patients .
出处
《医学影像学杂志》
2016年第3期389-392,共4页
Journal of Medical Imaging
基金
浙江省宁波市社会发展计划项目(2013C50019)
关键词
脊髓型颈椎病
磁共振成像
弥散
Cervical spondylotic myelopathy
Diffusion magnetic resonance imaging
