摘要
目的探讨对颅脑创伤性昏迷患者采用右正中神经电刺激进行治疗的临床疗效和价值,以期为临床有效治疗颅脑创伤性昏迷提供新的治疗思路和理论依据。方法采用前瞻性随机对照研究方法,将2013-11~2014-11期间该院神经外科收治的颅脑创伤性昏迷患者(89例)按照随机数字表分为对照组和观察组,对照组(43例)给予降颅压、营养神经、预防感染、防治应激性溃疡、维持水电解质平衡和支持对症、康复训练等常规综合治疗方法;观察组(46例)给予对照组治疗方法的同时采用右正中神经电刺激进行治疗。对比观察两组患者3个月时格拉斯哥昏迷量表(GCS)评分状况、生活质量、语言功能和运动功能情况。结果随访3个月时,观察组患者的生活质量、语言功能和运动功能情况、GCS预后评估显著高于对照组,差异均具有统计学意义(P<0.05)。结论采用右正中神经电刺激治疗颅脑创伤性昏迷患者,可以促进患者的神经功能恢复,减轻残疾程度,提高生活质量,可以获得满意的临床疗效。
Objective To explore the clinical therapeutic effect of electrically stimulating right median nerve on the patients with craniocerebral traumatic coma, and to provide a new therapeutic method and theoretical basis for the treatment of craniocerebral traumatic coma. Methods Eighty-nine patients with craniocerebral traumatic coma in our hospital from November 2013 to November 2014 were randomly divided into the control group and the observation group. The control group （n = 43 ） was given the conventional treatment methods including intraeranial decompres- sion, nerve nourishing, infection prevention, prevention and treatment of stress ulcer, maintain water and electrolyte balance symptomatic support and rehabilitati0n training. The observation group（n =46） was given the same conven- tional treatment method as tile control group besides the use of electrically stimulating right median nerve simultane- ously. The GCS score, quality of life, language function and movement function were compared between the two groups after a follow up of 3 months. Results The quality of life, language function, movement function and Glasgow prognostic assessment improved significantly in tile observation group than those in the control group after a follow up of 3 months （P 〈 0. 05）. Conclusion Electrical stimulation of right median nerve can promote the nervous functional recovery, reduce the degree of disability and improve t^e quality of life for the patient with craniocerebral traumatic coma.
出处
《中国临床新医学》
2016年第3期197-201,共5页
CHINESE JOURNAL OF NEW CLINICAL MEDICINE
基金
广西钦州市科学技术局科技攻关课题(编号:20113705)
关键词
颅脑创伤
昏迷
右正中神经
电刺激
神经功能
Craniocerebral trauma
Coma
Right median nerve
Electrical stimulation
Neurologicalfunction
