摘要
目的:观察中药佐治化疗性肝损伤恢复期内情况与安全性。方法:87例化疗且出现肝损伤患者随机数字表法分为治疗组(n=44)与对照组(n=43)。对照组常规治疗,治疗组在对照组常规治疗基础上加用生脉饮加味方佐治,分早晚2次温服,1剂/天,共2个月,比较两组治疗有效率、不同分级肝损伤改善率及不良反应发生率。结果:治疗组有效率高于对照组(P<0.05)。两组治疗前轻度肝损伤改善率的比较无统计学意义(P>0.05)、治疗组中度、重度肝损伤改善率均高于对照组(P<0.05)。两组不良反应发生率差异比较无统计学意义(P>0.05)。结论:中药佐治化疗性肝损伤恢复期内效果显著,肝损伤得到有效改善与修复,安全性高。
[ABSTRACT]Objective:To observe the injury in the recovery period and the efifcacy and safety of Chinese drugs on liver. Methods:87 cases of chemotherapy and liver injury were randomly divided into treatment group (n=44) and control group (n=43). The control group was given conventional treatment, the treatment group in the control group on the basis of conventional therapy combined with Shengmai Yin Katasa Ji, sooner or later, 2 times a day, 1 dose/day, a total of 2 months, compared two groups of treatment efifciency, different grades of liver injury improvement rate and incidence of adverse reactions. Results:The effective rate of treatment group was higher than that of control group (P<0.05). The two groups before treatment mild mild liver injury to improve the rate of no statistical signiifcance (P>0.05), the treatment group moderate to severe liver injury improvement rate were higher than those of the control group (P<0.05). There was no signiifcant difference in the incidence of adverse reactions between the two groups (P>0.05). Conclusion:Traditional Chinese medicine adjuvant chemotherapy of hepatic injury recovery period effect is remarkable, the liver injury get effective improvement and repair and high safety.
出处
《中国医药导刊》
2016年第3期284-285,共2页
Chinese Journal of Medicinal Guide
关键词
中药
化疗
肝损伤
恢复期
Medicine
Chemotherapy-induced liver injury
Hypochondriac
Toxicity