摘要
目的对齐拉西酮治疗精神分裂症的疗效进行观察分析。方法选取2014年10月~2015年8月我院接受临床治疗的精神分裂患者116例,随机分为试验组和对照组,试验组予以齐拉西酮治疗,对照组采用奥氮平治疗。对两组患者治疗前后的PANSS评分情况、不良反应发生情况进行比较。结果两组患者经治疗PANSS评分均较治疗前PANSS评分有所降低,但两组SPANSS评分降低情况相较无明显差异,不具有统计学意义。此外两组均有不良反应发生情况,从总发生率来看无较大差异。结论齐拉西酮和奥氮平在治疗精神分裂症方面均有一定疗效,但不良反应具体发生情况不同,应该根据患者不同特性进行合理选择,以提高安全性,使疗效得到最大发挥。
Objective Alignment geodon curative effect observation analysis for the treatment of schizophrenia. Methods Selected 116 cases of schizophrenia patients from October 2014 to August 2015 in our hospital, which were randomly divided into experimental group and the control group, for patients with ziprasidone treatment, control group treated with olanzapine. Before and after treatment in patients with two groups of PANSS scores of comparing, adverse reactions occur. Results Two groups of patients after treatment of PANSS score was PANSS score decreases, the SPANSS score lower case but two groups compared with no obvious difference, no statistical significance. In addition two groups all have adverse reactions occur, from the total incidence of no big difference.Conclusion Ziprasidone and olanzapine in the treatment of schizophrenia in all have certain effect, but adverse reactions to the specific situation is different, so should make reasonable choice according to different characteristics in patients with, in order to improve the security, make curative effect get maximum play.
出处
《中国继续医学教育》
2016年第6期157-158,共2页
China Continuing Medical Education
