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血浆D-二聚体、纤维蛋白原水平对NSCLC患者放疗后生存的影响 被引量:2

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摘要 目的观察非小细胞肺癌(NSCLC)患者血浆D-二聚体(DD)、纤维蛋白原(Fib)水平变化,并探讨其对放疗后生存期的影响。方法选择83例NSCLC患者为观察组,50例体检健康者为对照组,分别采用免疫比浊法和光学凝固法检测其血浆DD和Fib。观察组采用静态调强技术(IMRT)放疗,分析血浆DD、Fib对患者术后生存期的影响。结果观察组、对照组血浆DD分别为(555±239)、(232±182)ng/m L,血浆Fib分别为(3.93±2.37)、(2.48±2.44)g/L,两组相比,P均<0.05。观察组血浆DD水平高者中位生存期为9.7个月,短于血浆DD水平低者的17.8个月,P<0.05;血浆Fib水平高者中位生存期为13.4个月,短于血浆Fib水平低者的18.2个月,P<0.05。结论 NSCLC患者血浆DD和Fib水平升高,且放疗前血浆DD和Fib水平高者生存期缩短。
出处 《山东医药》 CAS 北大核心 2016年第6期40-41,共2页 Shandong Medical Journal
基金 河北省卫生厅科研基金资助项目(20120367)
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