摘要
目的探讨青年女性乳腺癌患者的临床病理特点。方法对76例青年女性乳腺癌(年龄≤35岁)的临床病理资料进行回顾性分析,并以85例同期老年女性乳腺癌(年龄≥65岁)为对照。结果青年组肿瘤直径在2 cm^5 cm之间者占61.8%,浸润性非特殊癌占78.9%,浸润程度T3~T4者85.5%,临床分期Ⅱ~Ⅲ期占73.7%,均高于老年组,其中T分期及p TNM分期和老年组比较差异有统计学意义(P<0.05)。雌激素受体(ER)、孕激素受体(PR)在老年乳腺癌中表达呈中度相关,在青年组中呈弱相关。结论青年女性乳腺癌组织学分级较差、分期较晚,恶性程度高,ER、PR表达低,临床要加强早期诊断和治疗。
Objective To investigate the clinical and pathological characteristics of two age groups of young and old patients with breast cancer.Methods The clinical and pathological data of 76 cases of young female breast cancer（age≤35 years）were retrospectively analyzed,and made 85 cases of elderly female breast cancer（age≥65years）over the same period as the control.Results In young group,the tumor diameter of 61.8% was 2.0cm-5.0cm,and the proportion of invasive non special carcinoma was 78.9%,the invasion of degree T3-T4 was 85.5%,the clinical stage of phase II - III was 73.7%,those were higher than elder groups,and the differences in T staging and p TNM staging were significant（P〈0.05）. The expression of ER and PR in elder breast cancer was moderately correlated（P〈0.05）,while in the young group it was weak（P〈0.05）. Conclusion Breast cancer of young female has the characteristics of poor histological grade,late clinical stage,high degree of tumor malignancy and low expression of ER and PR,clinical should strengthen early diagnosis and treatment.
出处
《基层医学论坛》
2016年第1期12-14,共3页
The Medical Forum
关键词
青年
乳腺癌
女性
病理学
免疫组织化学
Young people
Breast cancer
Female Pathology
Immunohistochemistry
