摘要
目的探讨帕金森病伴有精神障碍（PDPsy）患者的生活质量。方法采用配对病例对照试验,收集2013年7月至2014年7月来本院诊治的PDPsy70例（PDPsy组）,按照年龄性别匹配后选出对照组仅患帕金森病（PD）的70例（PD组）。比较两组患者的H-Y等级、睡眠、抑郁、焦虑、认知、生活质量。结果PD组患者的病情严重程度要低于PDPsy组患者的病情（χ2=10.88,P〈0.01）。PDPsy组的患者病程要比PD组的患者长（χ~2=17.46,P〈0.01）。PDPsy组的患者失眠以及日间思睡情况比PD组重（ESS：t=2.13,P=0.04;RBD：χ2=5.83,P=0.02）。两组患者焦虑情况差异无统计学意义（t=0.74,P=0.67）。PDPsy组抑郁状况要较仅有帕金森病患者严重（t=2.41,P=0.02）。两组患者在认知方面差异无统计学意义（t=0.58,P=0.99）。PDPsy组的患者的生活自理能力较PD组的患者要低（t=3.84,P=0.01）。结论帕金森病伴精神障碍的患者抑郁与睡眠、生活质量较差,需要照顾者以及医护人员更多关注。
Objective To explore the quality of life on the mental disorders with Parkinson＇s disease patient.Methods We had a matched case-control trial,to avoid the influence of age and gender on the study. There were 70 patients who had Parkinson with mental disorder on the PDPsy group among July 2013 to July 2014. The PD group were the patients having Parkinson without mental disorder. Compare the sleep,depression,anxiety,cognition,quality of life between the two groups. Results The patients＇ H-Y degree in PDPsy group was lower than that in PD group（ χ~2= 10. 88,P〈0. 01）. There was statistically significance in two group on diseaseduration（ χ~2= 17. 46,P0.01）. The patients on the PDPsy group had insomnia in the dark and sleepiness in the daytime than these on the PD group（ ESS： t = 2.13,P = 0. 04; RBD： χ~2= 5. 83,P = 0. 02）. And the patients on the PDPsy group were more depressive than that on the PD group（ t = 2. 41,P = 0. 02）. There were no statistically significance on anxiety and cognition between two groups. The ability of self-care life in PDPsy group was lower than that in PD group（ t = 3.84,P = 0.01）. Conclusion Patientshaving Parkinson ＇ s disease with mental disorders have poor quality of life. That should be pay more attention.
出处
《脑与神经疾病杂志》
2016年第3期152-155,共4页
Journal of Brain and Nervous Diseases
关键词
帕金森病
精神障碍
生活质量
Parkinson
Mental disorders
Quality of life
