摘要
目的探讨新辅助化疗联合肿瘤细胞减灭术对晚期卵巢癌的治疗价值。方法回顾性分析自2012年10月至2014年10月我院收治的78例晚期卵巢癌患者的临床资料。按治疗方法将患者分为治疗组和对照组。其中,对照组为自2012年10月至2013年9月,行肿瘤细胞减灭术的患者30例;观察组为2013年10月至2014年10月,先行新辅助化疗再行肿瘤细胞减灭术的患者48例。记录并比较两组患者的癌灶大小、腹水量、手术时间、术中出血量和住院时间。结果观察组患者的癌灶大小、腹水量、手术时间、术中出血量及住院时间均少于对照组,两组比较,差异有统计学意义(P<0.05)。结论新辅助化疗联合肿瘤细胞减灭术治疗晚期卵巢癌,能减少手术时间及术中出血量,缩短住院时间,改善患者生存质量,有积极的临床意义。
Objective To observe the c1inica1 effect of neoadjuvant chemotherapy combined with cytoreductive surgery in treatment of advanced ovarian cancer. Methods To make a retrospective study of 78 patients diagnosed with advanced ovarian cancer from Octo-ber 2012 to October 2014 in our department. Tota11y 30 patients between October 2012 and September 2013 were offered cytoreductive surgery（contro1 group）. Whi1e,48 patients between October 2013 and October 2014 were offered neoadjuvant chemotherapy combined with cytoreductive surgery（observation group）. The tumor size,ascites vo1ume,operation time,b1eeding vo1ume during operation and hospita1ization days of two groups were recorded and compared. Results The tumor size,ascites vo1ume,operation time,b1eeding vo1-ume during operation and hospita1ization days in observation group were significant1y 1ess than contro1 group（P 〈 0. 05）. Conclusion Neoadjuvant chemotherapy combined with cytoreductive surgery can 1essen operation time,reduce b1eeding vo1ume during operation, decrease hospita1ization days and improve 1ife qua1ity of patients with advanced ovarian cancer.
出处
《临床军医杂志》
CAS
2015年第12期1280-1282,共3页
Clinical Journal of Medical Officers
关键词
卵巢肿瘤
新辅助化疗
肿瘤细胞减灭术
Ovarian cancer
Neoadjuvant chemotherapy
Cytoreductive surgery
