摘要
目的探究心率变异性(HRV)及QT间期变异性(QTV)与急性心肌梗死(AMI)患者病情严重程度、预后及室性心律失常的关系。方法选取2013年1月—2014年9月在首都医科大学附属北京潞河医院心内科住院治疗的AMI患者86例作为AMI组,根据梗死部位分为前壁心肌梗死组45例和非前壁心肌梗死组41例;根据预后分为死亡组39例和存活组47例;根据室性心律失常分级量表分为室性心律失常组42例和非室性心律失常组44例。另选择同期体检正常者73例作为对照组。比较AMI组和对照组受试者、不同亚组AMI患者HRV指标〔时域分析指标:24 h内正常RR间期的标准差(SDNN)、24 h内相邻RR间期差值的均方根(RMSSD)、24 h连续5 min正常RR间期标准差的均值(SDNNIndex),频域分析指标:总频谱成分(TF)、低频成分(LF)、高频成分(HF)、LF/HF比值〕和QTV。结果 AMI组患者SDNN、RMSSD、SDNNIndex、TF、LF、HF及QTV均小于对照组(P<0.05);两组患者LF/HF比值比较,差异无统计学意义(P>0.05)。前壁心肌梗死组患者SDNN、RMSSD、SDNNIndex、TF、LF、HF及QTV小于非前壁心肌梗死组,LF/HF比值大于非前壁心肌梗死组(P<0.05)。死亡组患者SDNN、RMSSD、SDNNIndex、TF、LF、HF及QTV均小于存活组,LF/HF比值大于存活组(P<0.05)。室性心律失常组患者SDNN、RMSSD、SDNNIndex、TF、LF、HF及QTV小于非室性心律失常组,LF/HF比值大于非室性心律失常组(P<0.05)。结论 HRV及QTV与AMI患者病情严重程度、预后及室性心律失常的发生有关,其对病情严重程度、预后及室性心律失常的发生有一定的预测价值。
Objective To investigate the relationship between heart rate variability, QT interval variability and illness severity, ventricular arrhythmias of patients with acute myocardial infarction. Methods From January 2013 to September 2014, a total of S6 inpatients with acute myocardial infarction were selected as case group in the Department of Cardiology, Beijing Luhe Hospital Affiliated to Capital Medical University, and they were divided into A1 group （with anterior myocardial infarction, n = 45） and A2 group （with non -anterior myocardial infarction, n =41 ） according to the infarction locations, into B1 group （dead patients, n = 39） and B2 group （survived patients, n = 47） according to the prognosis, into C1 group （complicated with ventricular arrhythmias, n = 42） and C2 group （ did not complicated with ventricular arrhythmias, n = 44） according to theincidence of ventricular arrhythmias. A total of 73 healthy persons were selected as control group at the same time. Index of heart rate variability [ time domain index including 24 - hour standard deviation of normal RR intervals （ SDNN）, 24 - hour root - mean - square of differentials between adjacent RR intervals （ RMSSD ） , 24 - hour mean value of standard deviation of 5 - minute normal RR intervals （SDNNIndex） and frequency domain index including total frequency component （TF）, low frequency component （LF）, high frequency component （HF）, LF/HF ratio] and QT interval variability were compared between case group and control group, A1 and A2 group, B1 and B2 group, C1 and C2 group. Results SDNN, RMSSD, SDNNIndex, TF, LF, HF and QT interval variability of case group were statistically significantly lower than those of control group （P 〈0. 05 ）, while no statistically significant differences of LF/HF ratio was found between the two groups （P 〉 0. 05 ）. SI）NN, RMSSD, SDNNIndex, TF, LF, HF and QT interval variability of A1 group were statistically significantly lower than those of A2 group, while LF/HF rati
出处
《实用心脑肺血管病杂志》
2015年第12期1-4,共4页
Practical Journal of Cardiac Cerebral Pneumal and Vascular Disease
关键词
心肌梗死
心率变异性
QT间期变异性
室性心律失常
Myocardial infarction
Heart rate variability
QT interval variability
Ventricular arrhythmia
