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YKL-40与乳腺癌预后的研究进展 被引量：6

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摘要 乳腺癌是女性最常罹患的癌症,虽然大多数乳腺癌患者在早期就接受手术治疗、化疗或放疗,并且5年存活率达到95%,但是乳腺癌仍然是引起全球女性死亡的首要原因,所以用于监控高危患者肿瘤复发的生物标志物慢慢体现出了非常大的价值并且日益受到了人们的重视。最新研究发现人类软骨糖蛋白-39(YKL-40)可促进肿瘤细胞的存活、迁移、侵袭及血管生成,从而增强肿瘤的转移能力。提示其可能成为乳腺癌诊断和治疗的新靶点。就YKL-40在预测乳腺癌预后方面的研究进展进行综述。
作者 程浩 许军
机构地区 哈尔滨医科大学附属第四医院普外科
出处 《中国现代普通外科进展》 CAS 2016年第1期39-41,46,共4页 Chinese Journal of Current Advances in General Surgery
基金 黑龙江省自然基金面上项目(W2012RQ06)
关键词 YKL-40 乳腺肿瘤 预后 免疫组织化学
分类号 R735.9 [医药卫生—肿瘤]
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参考文献4

二级参考文献20

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共引文献62

同被引文献60

  • 1DeSantis C, Ma J, Bryan L, et al. Breast cancer statistics, 2013[J]. CA CancerJ Clin, 2014,64(1) :52 62. 被引量：1
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  • 9Hagdall EV, Ringshoh M, Hogdall CK, et al. YKL-40 tissue expression and plasma levels in patients with ovarian caneer[J]. BMC Cancer, 2009,9 : 8. 被引量：1
  • 10Kim SH, Das K, Noreen S, et al. Prognostic implications of im munohistoche-mically detected YKL40 expression in breast cancer[J]. World J Surg Oncol, 2007, 5 : 17. 被引量：1

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中国现代普通外科进展
2016年 第1期

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