摘要
目的:观察后循环缺血性眩晕肝阳夹痰证患者服用定眩汤前后血液动力学、血液流变学的变化。方法:将后循环缺血性眩晕肝阳夹痰证患者120例随机分为两组,治疗组60例予定眩汤口服,对照组予西比灵。两组均连续服药2周为1个疗程,2个疗程后观察TCD及血液流变学的变化。结果:1治疗后治疗组和对照组全血还原黏度(低切)及全血还原黏度(高切)、血浆黏度、红细胞聚集指数与本组治疗前比较均降低(P<0.05);治疗后治疗组与对照组全血黏度、全血还原黏度(低切)、全血还原黏度(高切)及红细胞聚集指数组间比较差异有统计学意义(P<0.05)。2治疗后治疗组及对照组基底动脉(BA)及左椎动脉(LVA)、右椎动脉(RVA)的收缩期血流速(Vs)、舒张期血流速(Vd)与本组治疗前比较均改善(P<0.05);治疗后治疗组与对照组"BA、RVA"的Vs、Vd及"LVA"的Vd组间比较差异有统计学意义(P<0.05)。结论:定眩汤治疗肝阳夹痰型后循环缺血性眩晕能改善脑部血流速度和血液流变学指标,疗效优于西比灵。
Objective： To investigate the efficacy of the Dingxuan decoction on hemodynamics and hemorheology in patients with posterior circulation ischemia vertigo of the Ganyang Jiayu type. Methods： 120 patients were randomly divided into two groups, 60 cases for each. The treatment group were treated with the Dingxuan decoction; and the control group were given Sibelium. A course of treatment lasted for 2 weeks. In 2 course, hemodynamics and hemorheology were observed. Results： After treatment, whole blood reduced viscosity, plasma viscosity and erythrocyte aggregation index in two groups were decreased; and those in the treatment group were better. After treatment, Vs and Vd of basilar artery, left vertebral artery and right vertebral artery were improved, and the treatment group was better; differences were statistically significant（P〈0.05）. Conclusion： The Dingxuan decoction on posterior circulation ischemia vertigo of the Ganyang Jiayu type could improve hemorheology, with good efficacy.
出处
《中医临床研究》
2016年第2期19-20,22,共3页
Clinical Journal Of Chinese Medicine
基金
江苏省中医药局科技项目[NO:LZ13204]
关键词
定眩汤
肝阳夹痰
后循环缺血
眩晕
经颅多普勒
血液流变学
The Dingxuan decoction
Ganyang Jiayu
Posterior circulation ischemia
Vertigo
Transcranial Doppler
Hemorheology
