摘要
目的探讨蓝黄视野和图形视觉电生理检查在原发性开角型青光眼早期诊断中的敏感性,为临床早期诊断提供依据。方法选择36例(52眼)可疑青光眼患者和32例(54眼)正常对照者进行蓝黄视野(B/YP)、图形视网膜点图(P-ERG)和图形视网膜诱发电位(P-VEP)检查。B/YP采用Humphrey-750型全自动电脑视野计进行检查,P-ERG和P-VEP采用RETIscan和RETI-port视觉电生理检查系统进行检测。结果 (1)可疑青光眼组中全视网膜光敏度均值为(16.39±3.26)d B,正常对照组的全视网膜光敏度均值为(21.65±2.14)d B,两组比较,差异有显著统计学意义(t=3.62,P<0.01)。可疑青光眼组的平均缺损值为(4.32±2.18)d B,正常组的平均缺损值为(2.85±1.83)d B,两组比较,差异有显著统计学意义(t=2.45,P<0.05)。(2)可疑青光眼组的N95振幅值为(8.16±2.53)μV,峰时值为(96.75±11.29)ms,正常对照组的N95振幅值为(9.82±2.25)μV,峰时值为(91.43±9.63)ms。振幅值与峰时值两组间比较,差异均有显著统计学意义(t=4.69,t=3.15,P<0.01)。(3)可疑青光眼组P100振幅为(8.73±2.54)μV,正常组的振幅为(10.58±2.26)μV。两组比较,差异有显著统计学意义(t=3.48,P<0.01)。可疑青光眼组P100的潜伏期为(102.36±3.29)ms,正常对照组的潜伏期为(98.28±2.75)ms,两组比较,差异有显著统计学意义(t=2.24,P<0.05)。结论 B/YP检查能发现白/白视野(W/WP)尚不能检出的视野缺损,PERG和PVEP对青光眼的早期变化有较高的敏感性,蓝黄视野检查联合图形视觉电生理对原发性开角型青光眼的早期诊断有较高的应用价值。
Objective To evaluate the clinical value of blue-on-yellow perimetry combined with visual electrophysiology on the early diagnosis of primary open angle glaucoma. Methods Thirty-six（ fifty-two eyes） suspected open angle glaucoma served as SOAG group,and thirty-two（ fifty-four eyes） normal subjects served as control group. B / Y P,P-ERG and P-VEP were examined in two groups. Results（ 1） The mean sensitivity of SOAG group and control group were（ 16. 39 ± 3. 26） d B and（ 21. 65 ± 2. 14） d B,there was a significant difference between two groups（ t = 3. 62,P〈0. 01）. The mean defect of SOAG group and control group were（ 4. 32 ±2. 18） d B and（ 2. 85 ± 1. 83） d B,there was a significant difference between two groups（ t = 2. 45,P〈0. 05）.（ 2） The amplitude and latency of N95 in SOAG group were（ 8. 16 ± 2. 53） μV and（ 96. 75 ± 11. 29） ms,and the amplitude and latency of N95 in control group were（ 9. 82 ± 2. 25） μV and（ 91. 43 ± 9. 63） ms. There was also significant difference in both the amplitude and latency（ t =4. 69,t = 3. 15,P〈0. 01）.（ 3） The amplitude and latency of P100 in SOAG group were（ 8. 73 ± 2. 54） μV and（ 102. 36 ± 3. 29） ms,the amplitude and latency of P100 in control group were（ 10. 58 ± 2. 26） μV and（ 98. 28 ± 2. 75） ms. There was significant difference in the amplitude and latency（ t = 3. 48,2. 24,P〈0. 05）. Conclusion Blue-on-yellow perimetry combined with the electrophysiological tests can be used in the early diagnosis of primary open-angle glaucoma.
出处
《临床军医杂志》
CAS
2016年第1期38-40,43,共4页
Clinical Journal of Medical Officers
关键词
蓝黄视野
视觉电生理
原发性开角型青光眼内容
Blue-on-yellow perimetry
Visual electrophysiological test
Primary open-angle glaucoma
