摘要
目的探讨踝肱指数（ABI）对短暂性脑缺血发作（TIA）患者继发脑梗死的诊断意义。方法通过对本院105例患者行ABI、颈动脉内膜中层厚度（IMT）及ABCD2评分检查,并对所有患者随访2个月,了解TIA患者继发脑梗死的发生情况,评估ABI对TIA患者的诊断价值。结果TIA患者颈动脉IMT为（0.92±0.14）mm,ABI0.95±0.20,随访2个月后TIA患者发生脑梗死16例（15.2%）。TIA无脑梗死患者与TIA伴脑梗死患者比较,颈动脉IMT、ABI差异有统计学意义（P=0.018,P=0.001）。颈动脉IMT增厚的TIA患者与颈动脉IMT正常的TIA患者相比,ABI明显降低,差异有统计学意义（P〈0.01）。ABCD2评分、颈动脉IMT、ABI曲线下面积分别为0.74（0.62-0.86）、0.77（0.65-0.89）、0.72（0.60-0.84）。结论 ABI为动脉粥样硬化的诊断指标,对TIA患者继发脑梗死的风险评估有意义。
Objective To study the value of ankle-brachial index（ABI）in diagnosis of secondary cerebral infarction in transient ischemic attack（TIA）patients.Methods The ABI and carotid intima-media thickness（IMT）in 105 TIA patients were measured and their ABCD2 scores were recorded.The patients were followed up for 2months to observe the incidence of secondary cerebral infarction and to assess the value of ABI in diagnosis of TIA.Results The carotid IMT and ABI were 0.92±0.14 mm and 0.95±0.20 respectively in the TIA patients.Cerebral infarction occurred in 16（15.2%）out of the 105 TIA patients during the 2-month follow up period.A significant difference was found in carotid IMT and ABI between TIA patients without cerebral infarction and those with cerebral infarction（P=0.018,P=0.001）.The ABI was significantly lower in TIA patients with thicker carotid IMT than in those with normal carotid IMT（P〈0.01）.The ABCD2 score,carotid IMT and the area under the ABI curve were 0.74（0.62-0.86）,0.77（0.65-0.89）,and 0.72（0.60-0.84）respectively.Conclusion ABI,as a diagnostic index of carotid atherosclerosis,plays a role in assessing the risk of secondary cerebral infarction in TIA patients.
出处
《中华老年心脑血管病杂志》
CAS
2016年第2期165-167,共3页
Chinese Journal of Geriatric Heart,Brain and Vessel Diseases
基金
重庆市医学科研计划项目(2011-2-546)
关键词
脑缺血发作
短暂性
脑梗死
颈动脉疾病
动脉粥样硬化
踝肱指数
ischemic attack
transient
brain infarction
carotid artery diseases
atherosclerosis
ankle-brachial index
