摘要
目的观察气滞胃痛颗粒与奥美拉唑联合治疗胃食管反流病的临床疗效。方法选取2014年1月—6月接诊的84例胃食管反流病患者,随机等分为对照组和观察组,对照组给予奥美拉唑等西药治疗,观察组在上述治疗基础上加用气滞胃痛颗粒治疗,观察2组的治疗效果。结果 2组患者临床治疗有效率相比,观察组88.0%高于对照组的64.29%,P<0.05,差异具有统计学意义;观察组内镜下有效率73.81%高于对照组的52.38%,P<0.05,差异具有统计学意义;观察组治疗后24 h食管PH<4的时间较治疗前减少数多于对照组,差异显著,P<0.05,具有统计学意义。结论气滞胃痛颗粒与奥美拉唑联合治疗胃食管反流病,能有效缓解患者症状,修复食管黏膜损伤,改善食管PH,值得临床推广。
Objective To observe the clinical curative effect of Qizhi Weitong granule combined with omeprazole in the treatment of gastroesophageal reflux disease. Methods Selecting 84 cases of gastroesophageal reflux disease patients in our hospital from January 2014 to June 2014, they were randomly divided into observation group and control group, and each group had 42 cases. The control group was given omeprazole treatment of Western medicine. The observation group was given Qizhi Weitong granule on the basis of the control group. The therapeutic effect of the two groups was observed. Results The clinical effective rate of the observation group was 88% which was higher than 64.29% of the control group, P〈0.05, and the difference was statistically significant. The endoscopic effect rate of the observation group was 73.81% which was higher than 52.38% of the control group, P〈0.05, and the difference was statistically significant. The difference of 24 h PH4 time of the observation group was higher than that of the control group, and the difference was significant, P〈0.05. Conclusion Qizhi Weitong granule combined with omeprazole in the treatment of gastroesophageal reflux disease can effectively alleviate the symptoms, repair of esophageal mucosal injury, improve esophageal pH, and is worthy of clinical promotion.
出处
《中国中医药现代远程教育》
2015年第24期70-71,共2页
Chinese Medicine Modern Distance Education of China
关键词
气滞胃痛颗粒
奥美拉唑
胃食管反流病
Qizhi Weitong granule
omeprazole
gastroesophageal reflux disease
