摘要
目的:探讨2型糖尿病视网膜病变(diabetic retinopathy,DR)与糖尿病的全身并发症的相关性。方法:分析2型糖尿病住院患者702例,将其分为NDR组、DR组两组,DR组又分为非增生性糖尿病视网膜病变(non-proliferative diabetic retinopathy,NPDR)组和增生性糖尿病视网膜病变(proliferative diabetic retinopathy,PDR)组,分析DR与糖尿病大血管并发症、糖尿病肾病(diabetic nephropathy,DN)、糖尿病周围神经病变(diabetic peripheral neuropathy,DPN),糖尿病周围血管性疾病(peripheral vascular disease of diabetes mellitus,PVD)、糖尿病足(diabetic foot,DF)、糖尿病酮症酸中毒(diabetic ketoacidosis,DKA)等糖尿病并发症的相关性。结果:DR的发生、发展与高血压、高血脂、颈部血管硬化、斑块,下肢动脉硬化、斑块,DN、DPN、DF及PVD等并发症有关。PDR与高血压、DPN关系密切。结论:血管内皮损伤、微循环障碍是DR及糖尿病的全身大、小血管并发症的共同病理基础。糖尿病患者出现全身并发症时,DR的患病率增加,尤其是合并高血压、DPN时,PDR的患病率增加。所以糖尿病患者尤其是出现全身并发症者必需定期行眼底检查,以早期发现、早期治疗DR,降低致盲率。
AIM：To investigate the correlation between systemic complications and diabetic retinopathy in the patients with type 2 diabetes mellitus.METHODS：Seven hundred and two hospitalized patients with type 2 diabetes were included.All patients were divided into two groups according to with or without retinopathy：NDR group and DR group.DR group was divided into group non-proliferative diabetic retinopathy（NPDR） and group proliferative diabetic retinopathy（PDR）.The relation between DR and other complications of diabetes,including diabetic macrovascular complications,diabetic nephropathy（DN）,diabetic peripheral neuropathy（DPN）,peripheral vascular disease of diabetes mellitus（PVD）,diabetic foot（DF）,diabetic ketoacidosis（DKA）,was analyzed.RESULTS：The development of DR was related to hypertension,hyperlipemia,carotid atherosclerosis and plaque,lower extremity arteriosclerosis and plaque,DN,DPN,DF and PVD.PDR was closely associated with hypertension and DPN.CONCLUSION：The prevalence of DR increased in the diabetic patients with systemic complications,especially,the increase of prevalence of PDR in the patients with hypertension and DPN.Vascular endothelial injury and microcirculatory disturbance are the common pathologic base for DR and other complications.Therefore,it is important to carry out the regular fundus examination in the diabetic patients,especially in those with systemic complication,in order to decrease the rate of blindness.
出处
《国际眼科杂志》
CAS
2016年第2期309-312,共4页
International Eye Science
基金
广东省科技计划项目(No.2013B021800185)
东莞市科技计划项目重点项目(No.20101051500102)~~
关键词
糖尿病
糖尿病视网膜病变
糖尿病并发症
diabetes mellitus
diabetic retinopathy diabetic complications
