摘要
目的减少化脓性扁桃腺炎治疗中抗生素的不合理使用。方法回顾性分析医院儿科门诊诊治的化脓性扁桃腺炎病例1 107例。根据抗生素使用疗程分为足疗程组及不足疗程组;根据抗生素使用种类分为阿奇霉素组与非阿奇霉素组。比较足疗程组与非足疗程组、阿奇霉素组与非阿奇霉素组,发病后3个内复发及并发症发生情况。根据其籍贯及国籍分为中国大陆组、港澳台组及外籍组,比较三组抗生素使用不足疗程例数,分析疗程不足的原因。结果足疗程组复发率较不足疗程组明显减少(P<0.05),非阿奇霉素组复发率较阿奇霉素组明显增多(P<0.05)。中国大陆组的不足疗程发生率比港澳台组及外籍组明显增多(P<0.05)。不足疗程主要原因为患者依从性不足,与部分医生对该病的疗程认识问题也有一定关系。结论使用抗生素治疗化脓性扁桃腺炎时应坚持足疗程治疗,同时加强对我国大陆民众宣传合理使用抗生素的知识。
Objective To reduce unreasonable use of antibiotics in acute suppurative tonsillitis cases. Methods Retrospective analyses of 1107 acute suppurative tonsillitis cases from the pediatric outpatient department were conducted. According to course of antibiotic treatment, these cases were divided into the group of full course of treatment and the group of insufficient course of treatment, According to the types of antibiotic, the subjects were divided into azithromyein group and non - azithromycin group. Three months after the onset of illness, the occurrence of complications and illness relapse between full course of treatment group and insufficient course group, azithromycin group and non - azithromycin group were analyzed. Meanwhile, the cases were divided into Chinese mainland group, Macao and Taiwan group, and foreign group according to their native places and nationalities. We compared the number of cases used insufficient course in these three groups and analyzed their reasons. Results The relapse rate was significantly lower in the full course treatment group compared with insufficient course treatment group （ P 〈 0. 05 ）, and significantly higher in non - azithromycin group compared with azithromycin group （ P 〈 0. 05 ）. The occurrence rate of insufficient course treatment in the Chinese mainland group was obviously higher than the Macao group, Taiwan group and foreign group （ P 〈 0. 05 ）. The main reasons for insufficient course of treatment were the insufficient patients＇ obedience and some doctors＇ poor understanding of the disease course. Conclusion A full course treatment with antibiotics on acute suppurative tonsillitis are strongly suggested. It may be of great significant to strengthen the awareness of reasonable use of antibiotics among the inland citizens.
出处
《现代医院》
2016年第1期62-64,共3页
Modern Hospitals
基金
广州市番禺区科研攻关项目(编号:2014-Z03-44)
关键词
化脓性扁桃腺炎
合理使用抗生素
疗程
依从性
Suppurative Tonsillitis
Reasonable Use of Antibiotics
Course of Treatment
Obedience
