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循环肿瘤细胞检测在胰腺癌患者中的研究现状及应用前景 被引量:9

Research status and application prospects of circulating tumor cells detection in patients with pancreatic cancer
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摘要 循环肿瘤细胞(CTCs)是一类可进入血液循环的肿瘤细胞,其与肿瘤的远处脏器转移关系密切。既往研究结果表明胰腺癌患者血液中可检测到CTCs,而且可能对胰腺癌的临床分期、评估预后及疗效监测有帮助。现对CTCs的检测方法及其在胰腺癌诊断、治疗及预后方面的研究进展作一综述。 Cireulati-ng tumor cells (CTCs) are tumor cells that have acquired the ability to enter the circulato- ry system; this cell population is ultimately responsible for the development of metastases in distant organs. Some previously reported studies of the clinical relevance of CTCs detection in pancreatic cancer patients. There is evidence that CTCs also helpful in determining tumor stage, assessing prognosis, monitoring therapy response in pancreatic cancer patients. Now this article review various detection procedures of CTCs, and its advancements of diagnosis, treatment and prognosis in pancreatic cancer patients.
出处 《中华实验外科杂志》 CAS CSCD 北大核心 2016年第1期262-264,共3页 Chinese Journal of Experimental Surgery
关键词 循环肿瘤细胞 胰腺癌 预后 Circulating tumor cells Pancreatic cancer Prognosis
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  • 1Dominic Fong,Patrizia Moser,Armin Kasal,Andreas Seeber,Guenther Gastl,Agnieszka Martowicz,Martin Wurm,Christine Mian,Peter Obrist,Guido Mazzoleni,Gilbert Spizzo.Loss of membranous expression of the intracellular domain of Ep CAM is a frequent event and predicts poor survival in patients with pancreatic cancer[J].Histopathology.2014(5) 被引量:1
  • 2Lu Han,Wei Chen,Qicheng Zhao.Prognostic value of circulating tumor cells in patients with pancreatic cancer: a meta-analysis[J].Tumor Biology.2014(3) 被引量:2
  • 3Putao Cen,Xiaoling Ni,Jingxuan Yang,David Y. Graham,Min Li.Circulating tumor cells in the diagnosis and management of pancreatic cancer[J].BBA - Reviews on Cancer.2012(2) 被引量:1
  • 4Maria T. Sandri MD,Laura Zorzino DSc,Maria C. Cassatella DSc,Fabio Bassi MD,Alberto Luini MD,Chiara Casadio MD,Edoardo Botteri PhD,Nicole Rotmensz PhD,Laura Adamoli PhD,Franco Nolè MD.Changes in Circulating Tumor Cell Detection in Patients with Localized Breast Cancer Before and After Surgery[J].Annals of Surgical Oncology.2010(6) 被引量:1

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